In vertebrate cells and some insect cells, there are not only chemical modifications at both ends of the final mRNA product prior to its engagement with ribosomes in the cytoplasm but cleavage of the primary transcript and reunion of selected polynucleotide stretches鈥擱NA:RNA splicing鈥攊s ...
Here we show that the plant TREX-2 complex promotes multiple steps in miRNA biogenesis, including transcription, processing and nuclear export. THP1 and SAC3A—the core subunits of TREX-2—interact and colocalize with RNA polymerase II to promote the transcription of MIR genes in the nucleoplasm...
aPrior to nuclear export, pre-mRNAs undergo multiple RNA processing steps. These steps include capping at the 5 ? end, splicing to remove introns, and polyadenylation at the 3 ?end. 在核出口之前, pre-mRNAs接受多个RNA处理步骤。 这些步包括加盖在5 ? 结束,接合去除introns和polyadenylation在3 ?末端...
Describe the process of DNA replication, protein synthesis (including transcription and RNA processing) and translation. Briefly compare the functions and steps of transcription and translation. Explain the initiation process of eukaryotic transcription. Describe two differences between transcription and ...
Moreover, quality control mechanisms are being discovered that monitor ribosome synthesis and degrade the RNA components of defective pre-ribosomal particles. 展开 关键词: Pre-rRNA processing pre-ribosomal particle snoRNP nuclear export quality control ...
Describe the process of DNA replication, protein synthesis (including transcription and RNA processing) and translation. Describe how RNA and DNA are used in mitosis. Describe the basic steps of DNA extraction. What are the actual steps in DNA replication? What enzymes are required and what are ...
R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi PathwayThe RNA interference (RNAI) pathway is initiated by processing long ... - 《Science》 被引量: 0发表: 2003年 Faculty Opinions recommendation of R2D2, a bridge between the initiation and effector steps of the...
Nucleic acid extraction and isolation is a vital first step in next generation sequencing. This is regardless of whether you are sequencing total RNA, genomic DNA, or various RNA types. The extraction method that’s used will depend on the starting material. It is crucial to c...
Coupling pre-mRNA processing to transcription on the RNA factory assembly line. It has been well-documented that nuclear processing of primary transcripts of RNA polymerase II occurs co-transcriptionally and is functionally coupled to ... KM Lee,WY Tarn - 《Rna Biology》 被引量: 45发表: 2013年...
The concentrations of transcription factors, as of intracellular proteins in general, may be regulated at any of the steps leading from DNA to protein, including transcription, RNA processing, mRNA degradation and translation. The activity of a transcription factor is often regulated by (de)...