Endometrial stem/progenitor cells are a type of stem cells with the ability to self-renew and differentiate into multiple cell types. They exist in the endometrium and form niches with their neighbor cells and extracellular matrix. The interaction between endometrial stem/progenitor cells and niches ...
Neural stem and progenitor cells (NSCs) give rise to the cellular diversity of the CNS. There is evidence both for and against differences in these cells based on the region of the brain in which they reside. Primary brain tumors mimic many aspects of NSC behavior. Recent data suggest that...
在SVZ的脑室表面,多纤毛的室管膜细胞组织成风车结构,形成脑脊液(cerebral spinal fluid,简称CSF)和神经干/祖细胞(neural stem/progenitor cells,简称NSPCs)生态位之间的细胞屏障。除了作为CSF和干细胞隔间的功能性屏障,室管膜细胞直接调节产后神经发生,负责通过脑室系统...
造血干细胞(Hematopoietic stem cells,HSCs)是一类具有自我更新和多系分化潜能的原始细胞,存在于骨髓、脐带血和外周血中。它们可以分化成各种类型的血细胞,包括红细胞、白细胞、血小板等,在人体造血系统的稳态维持中发挥了关键作用。 线粒...
One of the mechanisms for mobilization of hematopoietic stem cells and progenitor cells is alternation of adhesion molecules. We investigated the mobilizat... T Kikuta,C Shimazaki,E Ashihara,... - 《Experimental Hematology》 被引量: 237发表: 2000年 The canonical Wnt pathway shapes niches supportiv...
A differentiation method informed by developmental biology converts human pluripotent stem cells to engraftable hematopoietic stem and progenitor cells without the use of transgenes. Adam C. Wilkinson Marella F. T. R. de Bruijn News & Views18 Sept 2024 Nature Biotechnology P: 1-2 Dedifferenti...
Haematopoietic stem cells are progenitor cells that have the ability to both generate all types of blood cells, including those of the myeloid and lymphoid lineages, and to replace themselves. In adults, they mainly reside in the bone marrow. ...
The cyclical regeneration and remodeling potentials allude to the existence of stem/progenitor cells in the endometrium. There is increasing evidence that human endometrium contains small numbers of stem-like cells capable of self-renewal, multiple differentiation and tissue reconstitution. Although the ...
Cell Cycle Entry of Hematopoietic Stem and Progenitor Cells Controlled by Distinct Cyclin-Dependent Kinase Inhibitors The therapeutic promise of hematopoietic stem cells in medicine has been expanded as broader differentiation potential of the cells has gained experimental... C Tao,DT Scadden - 《Intern...
Mechanisms governing the maintenance of blood-producing hematopoietic stem and multipotent progenitor cells (HSPCs) are incompletely understood, particularly those regulating fate, ensuring long-term maintenance, and preventing aging-...