Cell therapy as a replacement for diseased or destroyed endogenous cells is a major component of regenerative medicine. Various types of stem cells are or will be used in clinical settings as autologous or allogeneic products. In this chapter, the progress that has been made to translate basic ...
干细胞疗法 干细胞疗法是通过利用对干细胞进行体外分离、培养、定向诱导分化等,能够培养出一种全新的、正常的、更年轻的细胞、组织、器官等。通过特殊的移植技术移植到体内,代替那些正常或非正常死亡的细胞,从而恢复机体功能。 原理/干细胞治疗 疾病发生的原理是细胞或组织变性、死亡,功能减弱或丧失,从而出现疾病。干细...
Offering a unique focus on translational research into stem cell therapies, Stem Cell Research & Therapy acts as a platform for global debate and discussion. ...
在细胞研究方面,从人体浅筋膜和脂肪组织中分离出 FDSCs 和脂肪来源干细胞(Adipose-derived Stem Cells,ADSCs),并进行培养和鉴定;运用 RNA 测序(RNA-seq)技术分析基因表达谱,找出差异表达基因;通过蛋白质免疫印迹(Western blot)、定量实时聚合酶链反应(qPCR)等实验检测基因和蛋白表达水平。在功能验证方面,利用体外血管...
因此,探索更为有效的方法来修复受损子宫内膜功能依旧十分迫切。近日,研究人员报道了人羊膜间充质干细胞(hAMSC)结合生物支架促进受损子宫内膜再生的方法,成功恢复大鼠IUA模型生殖能力。相关研究结果发表在Stem Cell Research & Therapy上。 ...
Cell therapy has been identified as an effective method to regenerate damaged tissue. Adult stem cells, also known as somatic stem cells or resident stem cells, are a rare population of undifferentiated cells, located within a differentiated organ, in a specialized structure, called a niche, which...
Mesenchymal stem cells (MSCs), the major stem cells for cell therapy, have been used in the clinic for approximately 10 years. From animal models to clinical trials, MSCs have afforded promise in the treatment of numerous diseases, mainly tissue injury and immune disorders. In this review, we...
Scientists hope it will be possible in future to take adult stem cells from a patient needing treatment and program them to return to an embryonic-like state. These 'pluripotent' stem cells could diversify into any tissue the patient needs, without any risk of tissue rejection by the immune ...
为了攻克这些难题,青岛大学的研究人员进行了深入研究,并在《Stem Cell Research & Therapy》期刊上发表了题为 “Heterogeneity of urine-derived stem cells and the potential role of exosomes in the treatment of severe steatotic liver ischemia-reperfusion injury” 的论文 。他们发现,SS-USCs 有着强大的组织修...
Stem cell therapyin aging results in improved physical activity, which is manifested by decreased weakness, less tiredness in the evening, improved gait, straightened back, increased work capacity during the day. Observed is also improvement of mental ability, which is demonstrated by quickened decisi...