The present invention provides an isolated cell obtainable from the CTX0E03 neural stem cell line for use in the treatment of a disorder associated with elevated levels of proinflammatory cytokines, where the disorder is selected from unipolar and bipolar depression, schizophrenia, obsessive compulsive...
As a source of hematopoietic stem cells for transplantation, the use of peripheral blood stem cells (PBSCs) has become routine and comparable to that of th... Scharf,E R. 被引量: 0发表: 2008年 Peripheral blood stem cells: In vivo biology and therapeutic potential Peripheral blood stem cell...
Neural stem cells and their use as therapeutic tool in neurological disorders. Brain Res. Brain Res. Rev. 48, 211–219 (2005). Article CAS PubMed Google Scholar Vescovi, A. L. & Snyder, E. Y. Establishment and properties of neural stem cell clones: plasticity in vitro and in vivo. ...
and other extraembryonic tissue are increasingly accepted as a high-quality source of cells for therapeutic use. The best-known application is the transplantation of hematopoietic stem cells (HSCT), while UCB has become an increasingly important graft source since UCB transplantation (UCBT) has...
ease of long-term storage, lower chance of thromboembolism, and readiness for immediate use. Recent studies have demonstrated that EVs from stem cells, mostly from mesenchymal stem cells (MSCs) from various tissues, have anti-inflammatory, anti-oxidative, anti-apoptotic, and proliferative role in ...
Therapeutic cloning refers to the use of SCNT to reprogram somatic cells into undifferentiated cells (pluripotent stem cells) for different therapeutic purposes, such as the treatment of degenerative diseases or traumatic injuries, or to correct genetically predisposed conditions. The major advantage of ...
Exploring the role of stem cells in cutaneous wound healing. Exp Dermatol. 2009;18:921–33. Article CAS PubMed Google Scholar Turner NJ, Badylak SF. The use of biologic scaffolds in the treatment of chronic nonhealing wounds. Adv Wound Care. 2015;4:490–500. Article Google Scholar ...
“Today’s results show many of the advances we have made in the use ofCRISPR-Cas9and the human technologies of pluripotentstem cellsand the amazing discoveries that have resulted,”. “Neuroscientists use these new tools for gene editing and molecular tools to develop potential therapeutic go...
Review, we survey advances in stem cell research and describe the cell types that are currently being used in the clinic or are close to clinical trials. Finally, we analyse the scientific rationale, experimental approaches, caveats and results underpinning the clinical use of such stem cells. ...
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