Stem Cell IsolationMicrofluidics for Stem Cell TherapyStem cell isolationSpringer USEncyclopedia of Microfluidics & Nanofluidics
Mesenchymal stem cell (MSCs) are adult multipotent progenitor cells, which exist in almost all tissues, and are assumed immunomodulators17,18,19,20. This function makes them the most prominent therapeutic candidate for autoimmune and inflammatory diseases, as they can inhibit dendritic and T cell p...
This report describes the isolation and in vitro expansion of human colon stem cells from normal tissues. Cells with high levels of the membrane receptor EPHB2 are shown to have characteristics of intestinal stem cells, and the authors optimize culture c
Ashkon G.Seyed-Safi,Julie T.Daniels 3.1The stem cell niche The idea that stem cell preservation and function is dependent on their interaction with specific anatomical sites was first introduced in the study ofhaematopoietic stem cellsand their relationship with the bone marrow (Schofield, 1978). ...
In recent years, stem cell therapy has become a very promising and advanced scientific research topic. The development of treatment methods has evoked great expectations. This paper is a review focused on the discovery of different stem cells and the potential therapies based on these cells. The ...
Stem cells possess the unique ability to differentiate into specialized cell types. These specialized cell types can be used for regenerative medicine purposes such as cell therapy. Myosatellite cells, also known as skeletal muscle stem cells (MuSCs), play important roles in the growth, repair, an...
Neural stem cells(NSCs) are self-renewing, multipotent cells that generate the main phenotypes of thenervous system[1]. The hallmark characteristics ofNSCsare its ability to proliferate and generate multiple cell lineages, such as neurons, astrocytes, andoligodendrocytesbothin vitroandin vivo[2]. ...
These findings prompted us to further probe the efficacy of CD4+ T cells expressing either TCR 1 or TCR 3. As antitumor efficacy was dependent on CD40L help for CD8+ T cells, we used the SCC VII parental cell line for all future experiments to rule out the contribution of CD8+ T cells...
potential of MSCs is achieved via suppression of T cell activation and inhibition of antigen-presenting cell (APC) maturation. Whereas, MSCs that do not tip the balance toward immunosuppression are prone to immunogenicity and result in immune detection and destruction, as debris from apoptotic MSCs ...
(Fig.1a). The protein abundance of the top 5 genes was validated in RAW 264.7 cells treated with CT26 or MC38-derived CM. c-Myc, Snai1, and Id1, but not Tcf4 and Id2, were found to be highly expressed in the colon cancer cell-derived CM-treated group compared to the control (...