StemSpanTM Lymphoid Progenitor Expansion Supplement (10X) 09915 5 mL StemSpanTM Lymphoid Differentiation Coating Material (100X) 09925 2 x 250 μL StemSpanTM T Cell Progenitor Maturation Supplement (10X) 09930 12.5 mL STEMdiff™ NK Cell Kit( # 100-0170) STEMdiffTM NK Cell Kit 组份...
Stem cell quiescence is generally considered as an inactive state with poised potential. Here, Khoa et al. find that quiescent embryonic stem cells actively maintain a dynamic reservoir of cells with unrestricted cell fate that converges onS-adenosylmethionine and H3K27me3 status. ...
TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion. Nature 571, 211–218 (2019). Article CAS PubMed PubMed Central Google Scholar Yao, C. et al. Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection. Nat. Immunol. 20, ...
Following this, tumor-derived exosomes can suppress anti-tumor immunity by carrying immunosuppressive molecules that inhibit T-cell activation and promote regulatory T-cell expansion. Indeed, this dual role of exosomes in suppressing immune responses while simultaneously promoting tumor growth emphasizes thei...
In recent years, stem cell therapy has become a very promising and advanced scientific research topic. The development of treatment methods has evoked great expectations. This paper is a review focused on the discovery of different stem cells and the pot
调节性T细胞(regulatory T cells,Treg)在免疫耐受中起着至关重要的作用,例如在干细胞移植治疗白血病等血液疾病中,较低的Treg与GVHD的发展有关。但是,Treg十分稀缺,需要寻找稳定的Treg替代来源来产生治疗用Treg。此前研究表明,间充质干细胞(mesenchymal stem cell,MSC)介导的免疫调节可能部分受Treg的诱导和驱动。
Stem cell nicheis a combination of cells, adhesion molecules, andECMwhose prime function is maintenance of the “stemness” state of the stem cell. 2. Stem cell niche is located in a special anatomical site in each organ, which is the optimum one for the biochemical needs of stem cells....
2024年3月7日,中国科学院分子细胞科学卓越创新中心惠利健团队在Cell Stem Cell上在线发表了文章Preclinical efficacy and safety of encapsulated proliferating human hepatocyte organoids in treating liver failure。这项研究实现了大规模...
Subsequent limbal stem cell transplantation requires an ex vivo expansion step and preserving cells in an undifferentiated state remains vital. In this report we seek to control the phenotype of limbal epithelial stem cells by the novel application of compressed collagen substrates. We have ...
Global stem cell market is growing at 10.20% CAGR to hit USD 22.21 billion by 2030, driven by growing demand for stem cell banking, regenerative treatment options, and rising R&D initiatives to develop stem cell therapies.