(2) measuring step, the LSC marker gene, suppressing the expression of a gene selected constructed test method, the LSC marker gene from the gene of 2-218 containing as an active ingredient, a substance capable of inhibiting the activity of the translation product of the gene or substance ...
之前的工作指出肠道胶质细胞可以通过分泌小分子物质来调控肠道上皮通透性,而这部分工作主要关注肌间丛肠道胶质细胞,而对于分布在粘膜下丛的却知之甚少。 不久前,来自加拿大多伦多儿童医院的Tae-Hee Kim研究组在Cell Stem Cell上发表题为Enteric glial ...
RESEARCH HIGHLIGHTS Intestinal stem-cell marker The first molecular marker of stem cells in the small intestine and colon has been identified in a study published in Nature. Clevers and colleagues found that the Wnt target gene Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5) ...
A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production How ribosomes differ in composition and function to regulate gene expression is poorly understood. Here, the authors show that ribosome composition changes during stem cell differentiation and identify a...
(2007). Identification of stem cells insmall intestine and colon by marker gene Lgr5.Nature449, 1003–1007. 12. Sangiorgi, E., and Capecchi,M.R. (2008). Bmi1 is expressedin vivo in intestinal stem cells.Nat. Genet.40, 915–920. 13. Michalopoulos, G.K.(2010). Liver regeneration...
1. Barker et al., 2007 Barker, N., van Es J.H., Kuipers, J., Kujala, P., van den Born M., Cozijnsen, M., Haegebarth, A., Korving, J., Begthel, H., Peters, P.J., and Clevers, H. (2007). ...
Stem Cell-Mediated Regeneration in the Human Thymus 20:09 Webinar Nature Research Round Table: Maintenance of Human Pluripotent Stem Cells In Vitro 21:01 Webinar From hPSC to Immune Cells: Reagents for hPSC-Derived Cell and Gene Therapies
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia. Cell Stem Cell. 2022 Aug 4;29(8):1213-1228.e8.2. Barker N, van Es JH, Kuipers J, et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature. 2007 449, 1003–1007.3...
Another type of stem cell, termed theinduced pluripotent stem cell(iPSC) has recently been elevated as the new improved stem cell therapy that has characteristics of both hESCs and MSCs. iPSCs are pluripotent because they have been reprogrammed to replicate gene expression observed in ESCs. Human...
11. Barker, N., van Es, J.H., Kuipers, J., Kujala, P., vanden Born, M., Cozijnsen,M., Haegebarth, A.,Korving, J., Begthel, H., Peters, P.J., and Clevers, H. (2007). Identification of stem cells insmall intestine and colon by marker gene Lgr5.Nature449, 1003–100...