Alternate-day Dosing with Statins 来自 国家科技图书文献中心 喜欢 0 阅读量: 38 作者:FI Marcus,AJ Baumgarten,WL Fritz,PE Nolan 摘要: The duration of the cholesterol-lowering effect of statins is considerably longer than the duration of the pharmacokinetic half-life of these drugs. The long ...
Statins have been around long enough that all are available in generic form. This was important to Drs. Yao and Noseworthy, and their research team, because prescription cost is a well-known barrier to medication adherence. They also were interested in seeing if ACC/AHA guidelines implemented in...
50,51 More than half of the tweets on statins (56.1%) were not health related. This finding is in agreement with other research27 that 41% to 66% of posts on diseases and conditions are nonmedical.27 We identified that 353 posts with a statin mention contain an adverse event report (...
Nearly 1 in 3 American adults lives with elevated LDL and fewer than half are being treated for the condition, which isa major risk factor for heart disease.
However, existing LAI medicines have a long pharmacokinetic half-life, low water solubility, and low target plasma concentrations. Oral half-life correlates with LAI half-life but is extended through flip-flop kinetics. In a basic sense, a drug cannot be cleared until it is absorbed so the ...
However, existing LAI medicines have a long pharmacokinetic half-life, low water solubility, and low target plasma concentrations. Oral half-life correlates with LAI half-life but is extended through flip-flop kinetics. In a basic sense, a drug cannot be cleared until it is absorbed so the ...
Thus, they concluded that there was no direct correlation between brain cholesterol level, as well as HMG-CoA activity with memory function regulation, although there is tangible link between plasma cholesterol level and AChE level, and long-standing plasma cholesterol alteration may be essential to ...