This research revealed that the elimination half-life (t½) of atorvastatin significantly increased to more than double that of healthy Egyptians (P < 0.001). Moreover, the clearance (CL) in this study was significantly lower than that in Egyptian volunteers (P < 0.05) [61]. ...
One study on statin use in an elderly population showed that after 6 months almost half of the patients stopped taking their tablets28. Although our study population was younger, we can probably assume that medication adherence was lower than prescription rates. Lastly, clinical outcome was ...
Abstract Importance Statins reduce the risk of major adverse cardiovascular events, but less than one-half of individuals in America who meet guideline criteria for a statin are actively prescribed this medication. Objective To evaluate whether nudges to clinicians, patients, or both increase initiation...
The chart below shows that for a Calcium score of 0 to 100, there is no benefit for taking a statin drug. For a score above 100, however, the chart shows considerable reduction in MACE (major adverse cardiac event) for the statin users. Notice cholesterol level is not mentioned in this ...
(NCEP), 40 million Americans should be taking them. Some researchers have even suggested – half-jokingly – that the medications should be put in the water supply, like fluoride for teeth. And it’s almost impossible to avoid reminders from the industry that the drugs are vital. A current...
Okazaki S, Yokoyama T, Miyauchi K, Shimada K, Kurata T, Sato H, Daida H: Early statin treatment in patients with acute coronary syndrome: demonstration of the beneficial effect on atherosclerotic lesions by serial volumetric intravascular ultrasound analysis during half a year after coronary event...
2023. "Comparative Analysis of High-Intensity versus Low-to-Moderate Intensity Statin Therapy in Patients Undergoing Rotational Atherectomy for Calcified Coronary Artery Disease" Life 13, no. 11: 2232. https://doi.org/10.3390/life13112232 APA Style Choi, S. -S., Jung, J., Her, S. -H...
respectively [21]. The 46.3% achievement rate of our study was lower than this report. However, considering the lower dose of our study protocol, achieving ≥50% reduction in LDL cholesterol in almost half of the study subjects might be considered acceptable. Moreover, it should be considered...