An important issue for stroke prevention is the identification and treatment of risk factors such as hypercholesterolaemia. The 4 reasons to test if the statins have a role in stroke prevention are: (i) a statistical link between elevated low density lipoprotein-cholesterol or decreased high ...
The role of cholesterol in the pathogenesis of stroke, the role of the treatment of hypercholesterolemia in the prevention of stroke have been controversed. The explanation was based on the heterogenous characteristics of stroke, on the relationship between several risk factors, and on the role of...
Stroke prevention, blood cholesterol, and statins The risk of stroke increases with age, and hence the disease particularly affects the elderly, who are also at high risk for coronary heart disease. Epidem... P Amarenco,PC Lavallée,J Labreuche,... - 《Acta Neurologica Taiwanica》 被引量...
(Pharmacology) any of a class of drugs, including atorvastatin and simvastatin, that lower the levels of low-density lipoproteins in the blood by inhibiting the activity of an enzyme involved in the production of cholesterol in the liver
Statins White matter hyperintensities Stroke Cognitive decline Introduction Confluent white matter hyperintensities (WMH) on magnetic resonance imaging (MRI) are common among elderly patients, and are closely associated with cognitive impairment and dementia [1, 2]. Confluent WMH tend to progress rapidly,...
Statins are a class of drugs often prescribed by doctors to help lower cholesterol levels in the blood. By lowering the levels, they help prevent heart attacks and strokes. Studies show thatstatinsmay reduce the risk ofheart attack,stroke, and even death from heart disease by about 25%. ...
No benefit was seen in early vs later statin treatment following stroke, according to a new trial; however, the mild severity of strokes and relatively low numbers are seen as key limitations.
Study suggests caution on statins after a bleeding stroke.The article discusses a study which suggests that taking statins may harm people who have had a hemorrhagic stroke in an outer lobe of the brain. It references a study by Steven M. Greenberg and colleagues published in the "Archives of...
A meta-analysis of trials showed that the greater the LDL cholesterol reduction, the greater the intima-media thickness and stroke risk reductions. Even if statins also have 'pleiotropic' effects, their main action seems to be through LDL reduction. The Heart Protection Study only included strokes...
OBJECTIVES: To determine by how much statins reduce serum concentrations of low density lipoprotein (LDL) cholesterol and incidence of ischaemic heart disease (IHD) events and stroke, according to drug, dose, and duration of treatment. D... MR Law,NJ Wald,AR Rudnicka - BMJ 被引量: 7328发表...