In recent years, several randomized, controlled trials (RCTs) and observational studies have reported increased risk for new-onset type 2 diabetes mellitus (T2D) with statin treatment, particularly with use of high-intensity statins that reduce low-density lipoprotein cholesterol (LDL-C) by 50% ...
Statin therapy and related risk of new-onset type 2 diabetes mellitus The use of statins for cardiovascular disease (CVD) prevention is clearly supported by clinical evidence. Although statin therapy is rather well tolerated,... M Ruscica,C Macchi,B Morlotti,... - 《European Journal of Interna...
A small but significant link between new-onset diabetes mellitus (NOD) and statin therapy was noted with rosuvastatin users in the Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin study. Since then multiple analyses have further confirmed this as...
For patients 40 to 70 years of age with type 2 diabetes, a moderate-intensity statin therapy should be initiated (Class I recommendation) For patients 40 to 70 years of age with type 2 diabetes, a high-intensity statin can be useful (Class IIa recommendation) based on risk assessment For ...
Screening for hypertension in adults: US Preventive Services Task Force reaffirmation recommendation statement. JAMA. 2021;325(16):1650-1656. doi:10.1001/jama.2021.4987ArticlePubMedGoogle ScholarCrossref 25. US Preventive Services Task Force. Screening for prediabetes and type 2 diabetes: US ...
Cognition in Type 2 Diabetes or Pre-diabetic Stages Risk for non-insulin-dependent diabetes in the normoglycaemic elderly is associated with impaired cognitive function. NeuroReport 1997; 8:1527–1530. Cross... EVD Berg,YD Reijmer,GJ Biessels - Humana Press 被引量: 3发表: 2009年 Statin Pres...
“The connection of statins with diabetes is a bit stronger," Tracy said. “But for those patients that we have on statins, we have to do the risk versus benefit for the very low chance of developing diabetes and the high positive benefit on their coronary or cerebral circulation.” ...
Lipid abnormalities, which are common in type 2 diabetes, predispose to a greatly increased risk of coronary heart disease. This characteristic dyslipidaemia includes decreased concentrations of high-density lipoprotein cholesterol (HDL-C), elevated triglycerides, and a small, dense, atherogenic form of...
Statin and Aspirin Therapy for the Prevention of Cardiovascular Events in Patients With Type 2 Diabetes Mellitus Patients with type 2 diabetes mellitus are at 2 to 4 times increased risk of cardiovascular events compared with those without diabetes, both among patient... JA Udell,BM Scirica,E Br...
Researchers also found that statin therapy may be associated with an approximately 0.2%risk for developing type 2 diabetes, primarily in patients who already have risk factors for it, such as a sedentary lifestyle or obesity. An American Heart Association scientific statement on statin treatment con...