In recent years, several randomized, controlled trials (RCTs) and observational studies have reported increased risk for new-onset type 2 diabetes mellitus (T2D) with statin treatment, particularly with use of high-intensity statins that reduce low-density lipoprotein cholesterol (LDL-C) by 50% ...
David Morris There is strong evidence that early-onset type 2 diabetes (commonly defined as that occurring in people under the age of 40 years) is a m...
Methods One hundred and sixty-eight type 2 diabetes patients with hyperlipoidemia were randomly divided into 4 groups, Group A received fluvastatin, Group B received lovastatin, Group C received provastatin and Group D received simvastatin. The therapeutic effects and cost-effectiveness were compared ...
www.nature.com/scientificreports OPEN Circulating long-non coding RNAs as biomarkers of left ventricular diastolic function and remodelling received: 30 June 2016 accepted: 26 October 2016 Published: 22 November 2016 in patients with well-controlled type 2 diabetes D. de Gonzalo-Calvo1,2, F....
Type 2 diabetes mellitus (T2DM) accounts for around 90% of all cases of diabetes. In T2DM, the response to insulin is diminished, and this is defined as insulin resistance. During this state, insulin is ineffective and is initially countered by an increase in insulin production to maintain gl...
et al. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat. Genet. 41, 703–707 (2009). Article CAS Google Scholar Sattar, N. et al. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials....
Overall cognition, memory, and executive function was found to be significantly better in statin users (p < 0.0008). This suggests a positive effect of statins on cognitive function of type 2 diabetes patients that is independent of cholesterol levels. 展开 ...
[关键词]伊班膦酸钠;辛伐他汀;2型糖尿病;骨质疏松[中图分类号]R587.1 [文献标识码]A [文章编号]1671 6264(2014)05 0601 04doi:10.3969/j.issn.1671 6264.2014.05.014Clinicalstudyontreatingtype2diabetesmellituscomplicatedwithosteoporosisbyibandronatecombinedwithsimva...
Numerous trials have investigated the efficacy of add-on ezetimibe therapy for patients with type 2 diabetes and not controlled by statin therapy. The published data highly suggest that patients with type 2 diabetes may be more likely to benefit from ezetimibe/statin combination therapy. However, ...
Diabetes is among one of the leading causes of death in the United States. This dissertation seeks to identify psychosocial and structural factors that influence self-care and health care utilization in Latino and African American men with diabetes on regional and national levels. My dissertation als...