STAT5 Luc萤光素酶报告基因质粒(STAT5 luciferase reporter plasmid)是翌圣生物自主研发的用于检测STAT5转录活性水平为目的的报告基因。信号转导子和转录激活子(Signal transducer and activator of transcription, STAT)是酪氨酸激酶JAK-STAT信号途径中的重要环节,通过这一途径细胞信号可以从细胞外传递到细胞内,使相关基因...
The STAT5 (Signal transducer and activator of transcription 5) Luciferase Reporter U937 cell line monitors STAT5-mediated signal transduction pathways in the human monocyte cell line U937. It contains a firefly luciferase gene driven by STAT5 response elements located upstream of the minimal TATA pro...
STAT5-Luc荧光素酶报告基因(报告基因质粒)(STAT5 Luciferase Reporter Plasmid)是翊圣生物自主研发的用于检测STAT5转录活性水平为目的的报告基因。Stat5是信号转导和转录活化蛋白(signal transduction and activator of transcription,Stat)家族的重要成员,参与了Jak/Stat信号通路调控。Stat5能够影响细胞的增殖、分化、存活...
英文名称:STAT5 luciferase reporter plasmid 产品货号:SY0112产品规格:1μgSTAT5荧光素酶报告基因(报告基因质粒)(STAT5 luciferase reporter plasimd)是用于检测STAT5转录活性水平为目的的报告基因。Stat5是信号转导和转录活化蛋白(signal transduction and activator of transcription,Stat)家族的重要成员,参与了Jak/...
Luciferase reporter assays and mutational analyses unequivocally showed that STAT5 binds to the miR-33-5p promoter element, thereby modulating miR-33-5p transcription in response to MG infection. Ultimately, the overexpression of STAT5 led to an elevation in miR-33-5p expression while concurrently ...
STAT5 LUCIFERASE REPORTER PLASMID (STAT5-LUC荧光素酶报告基因质粒)推荐供应商 我要询价 上海钰博生物科技有限公司 联系电话:021-60514606 电子邮件:shybio@126.com CB指数:58 网址:www.ybio.net 相关信息:产品目录(6967)用户评价 中文名称:STAT5 luciferase reporter plasmid (STAT5-Luc荧光素酶报告基因质粒) ...
Luciferase reporter assay The promoter of PD-L1, HK1, PFKP or PDHA amplified by ClonExpress MultiS One Step Cloning Kit (Vazyme, C113-02) was inserted into the pGL3-Basic vector. For 293FT cell transfection, cells were co-transfected with pRL-TK, pGL3 empty vector or pGL3 vector containing...
Additionally, STAT5 was validated as a direct target of miR-221 in dual-luciferase reporter vector assays. MiR-221 restoration and STAT5 knockdown in K562/G cells increased the sensitivity of CML cells to imatinib by reducing the Bcl2: Bax ratio. Collectively, our data suggested that miR-221...
24 h after transfection on day 2. The cells were then harvested and subjected to the Luciferase Reporter Assay. Statistics Paired Student’st-tests (two-tailed, equal variance) and one-way ANOVA were performed to analyze all the densitometry data. One-way ANOVA was performed to analyze the...
Gene set enrichment analysis of TCGA dataset indicated significant enrichment of the IL2–STAT5 signaling in MGP‐high GC patients. Immunofluorescence staining and immunoprecipitation showed that MGP binds to p‐STAT5 in the nuclei of GC cells. Furthermore, ChIP‐qPCR and luciferase reporter assays ...