STAT5 Luc萤光素酶报告基因质粒(STAT5 luciferase reporter plasmid)是翌圣生物自主研发的用于检测STAT5转录活性水平为目的的报告基因。信号转导子和转录激活子(Signal transducer and activator of transcription, STAT)是酪氨酸激酶JAK-STAT信号途径中的重要环节,通过这一途径细胞信号可以从细胞外传递到细胞内,使相关基因...
STAT5-Luc荧光素酶报告基因(报告基因质粒)(STAT5 Luciferase Reporter Plasmid)是翊圣生物自主研发的用于检测STAT5转录活性水平为目的的报告基因。Stat5是信号转导和转录活化蛋白(signal transduction and activator of transcription,Stat)家族的重要成员,参与了Jak/Stat信号通路调控。Stat5能够影响细胞的增殖、分化、存活...
英文名称:STAT5 luciferase reporter plasmid 产品货号:SY0112产品规格:1μgSTAT5荧光素酶报告基因(报告基因质粒)(STAT5 luciferase reporter plasimd)是用于检测STAT5转录活性水平为目的的报告基因。Stat5是信号转导和转录活化蛋白(signal transduction and activator of transcription,Stat)家族的重要成员,参与了Jak/...
STAT5 LUCIFERASE REPORTER PLASMID (STAT5-LUC荧光素酶报告基因质粒)推荐供应商 我要询价 上海钰博生物科技有限公司 联系电话:021-60514606 电子邮件:shybio@126.com CB指数:58 网址:www.ybio.net 相关信息:产品目录(6967) 用户评价 中文名称:STAT5 luciferase reporter plasmid (STAT5-Luc荧光素酶报告基因...
The Bcl-X reporter plasmid (pGL2-1.2-luciferase27) was a gift from Paul Coffer (AZG, Pulmonary Diseases, Utrecht, The Netherlands). The expression vectors for protein kinase inhibitor (PKI) and mutant PKI (pRSV-PKI-Ver2 and pRSV-PKImut-Ver2) were kindly provided by R. A. Maurer (...
pGL3-basic or pGL3-PD-L1 promoter plasmid followed by luciferase activity determination. The medium without glucose was applied for 6 h to remove lactate, and then cells were treated with or without 10 mM lactate for another 24 h in the medium without glucose until luciferase activity de...
We next investigated the potential mechanism by which P-STAT5 modulates NPM1 expression. We first explored the impact of P-STAT5 on transcriptional activities of NPM1 gene by transfecting cells with the vector containing a NPM1 promoter driving luciferase reporter (pGL3-Luc-NPM1). Compromising ...
Cells were harvested, and DpnI (B) or luciferase (C) assay was done as described in “Materials and methods.” Arrow in (B) indicates the replicated plasmid. To analyze the mechanism of lack of replication and transcription-stimulating activity of these mutants (Δ683, Δ721, and Y699F),...
1a). Transfection of luciferase reporter plasmids to measure interferon-stimulated response element (ISRE) promoter activation following IFN stimulation3 showed IFN did not induce luciferase expression in these cells, but this was restored by co-transfection of a Homo sapiens STAT2 expression plasmid ...
Furthermore, the luciferase reporter system was used to verify whether miR-190a directly targets PTHLH. We analyzed the effect of miR-190a on the luciferase activity of vectors containing normal binding sites (PTHLH-wt) as well as artificially mutated vectors (PTHLH-mut). It was found that ...