Clinical Dementia Rating ScaleWith the prospect of prevention trials for familial Alzheimer's disease on the horizon, understanding the natural history of the illness has never been so important. Earlier this year in The Lancet Neurology , Acosta-Baena and colleagues published the results of the ...
then the entire colon may need to be removed. Most colon cancer surgery will not result in a colostomy (piece of colon is diverted and opens through portion of the abdominal
Like colon cancer, the prognosis and treatment of rectal cancer depend on how deeply the cancer cells have invaded the rectal wall and surrounding lymph nodes (its stage, or extent of spread). However, although the rectum is part of the colon, the location of the rectum in the pelvis poses...
found that 30% of trials involved behavioral “run-ins” (i.e., periods in which potential participants had to demonstrate adherence to specific behavioral tasks) and up to four pre-enrollment steps, likely further limiting participation and adversely impacting generalizability of study findings [23...
This study attempts to determine the relative contribution of blood pressure at different life stages across the early-life course from infancy to young
In recent years, several clinical trials have revealed the remarkable benefits of the relatively new class of diabetes drugs—called sodium-glucose cotransporter-2 (SGLT2) inhibitors—for chronic kidney disease. These medications treat both diabetes and diabetic CKD, as well as non-diabetic CKD. The...
To investigate prognostic significance of clinical and pathological stages in patients with locally advanced rectal carcinoma treated with neoadjuvant chemoradiotherapy (neo-CRT) and total mesorectal excision. 210 patients with locally advanced rectal ca
Clinical trials are always in progress to look for new therapies or combinations of therapies for people with all types and stages of lung cancer. Participating in such a study is another treatment option. Lung Cancer Follow-up Following surgery for operable lung cancer cases, there is an increa...
HPV infection is very common and does not lead to cancer in the majority of cases. Genital infections with HPVs typically cause no symptoms and go away on their own. Sometimes, however, the infection persists. Precancerous changes or ultimately cervical cancer only arises when there is persiste...
In addition to the unavoidable onset of motor complications, the physician’s efforts are further undermined by the progressive reduction of LD’s therapeutic efficacy as well as the frequent side effects. In addition to the dynamically changing therapeutic guidelines, clinical tri...