ovarian cancermicroRNAscirculating biomarkerdiagnosispersonalized therapyBackground: Ovarian cancer (OC) remains the deadliest gynecological malignancy, despite significant treatment advances. The absence of early detection tests results in advanced-stage diagnosis for 70% of OC cases. MicroRNAs (miRNAs) are ...
Ovarian cancer is a malignant tumor affecting the ovaries. It may be of the primary character when the main center is located in the ovarian tissues. It may also be of secondary character with the center in any part of the body. Carcinoma (70 percent of all malignant tumors), germ cell ...
Genetic mutations may cause cancer. For example, mutations of genes BRCA1 and BRCA2 (linked to an increased risk of breast and ovarian cancers) can inhibit the body’s ability to safe-guard and repair DNA. Copies of these mutated genes can be passed on genetically to future generations, lea...
Symposium no. 11 New approaches to cancer diagnosis and managementAdvanced stages of ovarian adenocarcinoma: High response rate with high dose CAP and half body radiation : E. Schejter, I. Brenner∗, E. Tal, and H. Zakut. The Dept. of Ob. Gyn., The Edith Wolfson Med. Center, ...
Women have a 1 in 75 chance of developing the illness during their lifetime. The five-year survival rate is 47.6%. Treatment for ovarian cancer is very effective when the cancer is caught at an early stage. Quick Facts About Ovarian Cancer Linked to occupational and secondhand asbestos ...
However, tumor markers are also made by normal cells in the body, and levels may increase significantly in noncancerous conditions. Examples of tumor markers include: Prostate-specific antigen (PSA) for prostate cancer Cancer antigen-125 (CA-125) for ovarian cancer Calcitonin for medullary thyroid...
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The only curative cancer treatment is the surgical removal of all cancer, occasionally the removal of the entire pancreas, and a pancreatic transplant; however, few patients are eligible for a pancreatic transplant. Chemotherapy after surgery can lower the chances of the cancer returning. ...
Malignant germ cell cancer of the ovary (type of ovarian cancer) is a very rare type of cancer. Malignant ovarian germ cell cancer is a term used to describe a group of heterogeneous rare tumours affecting the ovaries. These tumours start in the egg (ovum) producing cells of the ovary, ...
We perform a comprehensive multi-omics analysis of 448 samples from 190 UC patients, covering the whole spectrum of disease stages and grades. Proteogenomic integration analysis indicates the mutations of HRAS regulated mTOR signaling to form urothelial papilloma rather than papillary urothelial cancer (...