Clarifying this would benefit all, including patients, care partners, primary care providers, regulators, and payers, and would enhance our understanding of the relationship between clinical trial endpoints and assessments used in everyday practice. At present, there is a wide range of assessment ...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder marked by progressively worsening stages of progression. People with ALS experience muscle weakness and neurological dysfunction, but initial symptoms are typically mild and affect only one part of the body. As the disease becomes more ...
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. Autoimmune diseases are illnesses that develop when the body's immune system attacks its tissues. The immune system contains a complex organization of cells and antibodies designed normally to "seek and...
In particular, the use of live (i.e., “human”) versus automated reminders [34], along with the use of shorter, more frequent assessment tasks versus longer questionnaire batteries [35] and passive measurement (i.e., through smartphone applications or wearable sensors) [40] can reduce part...
For example, many people live to over 100 years of age and never develop Alzheimer's disease. What's the difference between Alzheimer's disease and dementia? Dementia is a syndrome characterized by: impairment in memory, impairment in another area of thinking such as the ability to organize ...
While it is true that we don’t have a crystal ball to help us see into the future, we do have a lot of science on our side that can help us get a glimpse. So it’s not a trick, just basic genetics, which tells us that tall parents typically have tall children, and vice versa...
Electronic health record (EHR)-based biobanks contain rich information of genetic variants, lab tests, and clinical diagnosis, which can be used to identify preclinical individuals at risk for progression9. As germline genetic information usually does not change during the lifetime, it is an ideal...
Recrudescent infections with the human malaria parasite, Plasmodium falciparum, presented traditionally the major setback of artemisinin-based monotherapies. Although the introduction of artemisinin combination therapies (ACT) largely solved the problem, the ability of artemisinin to induce dormant parasites ...
Detection and localization of surgically resectable cancers with a multi-analyte blood test. Science. 2018;359(6378):926-930. doi:10.1126/science.aar3247PubMedGoogle ScholarCrossref 28. ClinicalTrials.gov. IMPROVE Intervention Trial Implementing Non-invasive Circulating Tumor DNA Analysis to Optimize ...
The tissue sealants pipeline market research report provides a comprehensive understanding of the pipeline products along with their comparative analysis at various stages of development. The report also includes information about the territories wherein