Analysis of neoadjuvant nivolumab and ipilimumab for clinical stage III melanoma using the SWOG S1801 event-free survival definition.doi:10.1200/JCO.2024.42.16_suppl.e2156362211e21563#Background:Perioperative pembrolizumab to advanced melanoma, as shown SWOG S1801 trial, was associated with a ...
Dr. Ayers said: “Around 150,000 people in the UK survive the acute stage of a heart attack each year. Feelings of fear, anxiety and depression are common after such an event. The findings of this study suggest that a high proportion experience very severe distress – this has the ...
“Keytruda is the first immunotherapy to show positive results for event-free survival in patients with high-risk early-stage TNBC, a particularly aggressive form of breast cancer,” said Roy Baynes, MMed, PhD, FCP, senior vice president, head of global ...
(2010). Analysis of time-to-event data under a two-stage survival adaptive design in clinical trials. Journal of Biopharmaceutical Statistics 20: 705–719. :Lu Q, Tse SK, Chow SC. Analysis of time-to-event data under a two-stage survival adaptive design in clinical trials. J Biopharm ...
Kwak MJ, Jung SH. Phase II clinical trials with time-to-event endpoints: Optimal two-stage designs with one-sample log-rank test. Statistics in Medicine 2013; 33:2004-2016.M. Kwak, S.H. Jung, Phase II clinical trials with time-to-event endpoints: optimal two-stage designs with one-...
Simon's two-stage design is one of the most commonly used methods in phase II clinical trials with binary endpoints. The design tests the null hypothesis that the response rate is less than an uninteresting level, versus the alternative hypothesis that the response rate is greater than a ...
Analysis of time-to-event data under a two-stage survival adaptive design in clinical trials. J Biopharm Stat. 2010;20(4):705–19.Lu, Q., Tse, S.K., and Chow, S.C. (2010). Analysis of time-to-event data under a two-stage survival adaptive design in clinical trials. Journal of...
Downregulation of caspase-9 is a frequent event in patients with stage II colorectal cancer and correlates with poor clinical outcome. Colorectal Dis, 12, 1213-8.Shen, X.G., C. Wang, Y. Li, L. Wang, B. Zhou, B. Xu, X. Jiang, ...