Survival rates are like the view from 30,000 feet: They're broad but not super-detailed. These figures are estimates of how long people with a certain type of cancer and stage might live. Stage IV colon cancer has a relative 5-year survival rate of about 14%. This means that about 14...
COLON cancerMETASTASISLIVER tumorsGENE expressionStage 4 colon cancer (CC) presents a significant global health challenge due to its poor prognosis and limited treatment options. Tetraspanins, the transmembrane proteins involved in crucial cancer processes, have recently gained attention as...
They found that the new tumor size-node-metastasis classification could accurately evaluate prognosis and provide very powerful discrimination of patients’ OS, as compared with TNM classification. Until now, few studies have incorporated tumor size into the staging system of colon cancer. In the ...
8.2.3.2.4DNA base excision repair genes DNA repair mechanisms such as MMR or base excision repair (BER) affect tumor characteristics and prognosis. They also determine chemotherapeutic response. Defective MMR leads to chemoresistance in colon cancer. The BER gene, that is, the MYH gene is respons...
The GradientBoosting model’s AUC value was 0.734, which can still predict cancer prognosis (See Table 2 and Fig. 4). Figure 4 Machine learning algorithm for prediction of Recurrence of colorectal cancer after tumor resection in testing group (Contains four machine learning algorithms, such as: ...
Deschoolmeester, V., Smits, E., Peeters, M.et al.Status of Active Specific Immunotherapy for Stage II, Stage III, and Resected Stage IV Colon Cancer.Curr Colorectal Cancer Rep9, 380–390 (2013). https://doi.org/10.1007/s11888-013-0182-5 ...
Hepatitis C virus (HCV) causes debilitating liver diseases, which may progress to cirrhosis and cancer, and claims 500,000 annual lives worldwide. While HCV epidemiology, pathophysiology, and therapy are being deeply studied, rare attention is given to r
Dr. Berri: Patients we treat have stage 4 metastatic cancer that has spread to the abdominal or peritoneal cavity. Patients who are eligible for evaluation are any patients who have tumors of the appendix, ovary, colon, rectum, stomach or small intestine. It also treats primary tumors of the...
doi:10.1001/jamasurg.2023.8015 Key Points Question Can the accuracy of prognosis estimation be improved using a pathomics signature to identify patients who can benefit from adjuvant chemotherapy for stage III colon cancer? Findings In this prognostic study including 785 patients with stage III...
Conversion therapy for gastric cancer (GC) has been the subject of much recent attention. It is defined as a surgical treatment aiming at an R0 resection a