Stage 4 colon cancer (CC) presents a significant global health challenge due to its poor prognosis and limited treatment options. Tetraspanins, the transmembrane proteins involved in crucial cancer processes, have recently gained attention as diagnostic markers and therapeutic targets. H...
They found that the new tumor size-node-metastasis classification could accurately evaluate prognosis and provide very powerful discrimination of patients’ OS, as compared with TNM classification. Until now, few studies have incorporated tumor size into the staging system of colon cancer. In the ...
When one is diagnosed to have Stage IV cancer, the immediate concern is if the person will be able to survive the disease. This concern, also medically known as the prognosis, depends on many factors, including availability of treatment and one's general health condition. Knowing what stage o...
Stage 4 colon cancer, or what is also known as colorectal cancer, is the last stage of one going through the effects of this disease. Find out here about the life expectancy of patients, and what symptoms come forth with this ailment… The large intestine is a long winding muscular tract,...
Stage IV breast cancer is metastatic breast cancer (MBC). Because real-world data are lacking in China, our research attempts to explore the effect of locoregional surgery on the prognosis of patients with MBC. A total of 987 patients from 10 hospitals and 2 databases in East China (2004–...
ABCC2, ABCG2 and SOX2 may be promising prognostic markers for patients with CC receiving FOLFOX-4 therapy. 展开 关键词: colon cancer, ATP-binding cassette transporter, cancer stem cell, adjuvant chemotherapy, prognosis DOI: 10.3892/ol.2019.10234 年份: 2019 ...
8.2.3.2.4DNA base excision repair genes DNA repair mechanisms such as MMR or base excision repair (BER) affect tumor characteristics and prognosis. They also determine chemotherapeutic response. Defective MMR leads to chemoresistance in colon cancer. The BER gene, that is, the MYH gene is respons...
Different opinions exist on the relationship between the C-reactive protein-to-albumin ratio (CAR) and the prognosis of colon cancer. This study is aimed at evaluating the relationship between CAR an...
Can immunohistology improve detection of lymph node metastases in large bowel cancer?Dis Colon Rectum 1989;32:99–102.PubMedCrossRef 9. Broll R, Schauer V, Schimmelpennig H, et al. Prognostic relevance of occult tumor cells in lymph nodes of colorectal carcinomas.Dis Col Rectum 1997;40:...
(data not shown). In addition, postoperative adjuvant chemotherapy is mandatory for patients with stage III colorectal cancer, and the clinical utility of this finding based on the receipt of adjuvant chemotherapy was also investigated. We analysed the prognosis of patients receiving adjuvant ...