Dynamics of hepatic fibrosis (stage) and necroinflammation (grade) in hepatitis B virus infection: Dong J Kim, Hallym University, Chunchon, Kangwon-Do South Korea; Jin B Kim, Young H Choi, Choong K Park, Jae Y Yoo, Hallym University, Chunchon South Korea...
Hepatic fibrosis is a common pathological process of chronic hepatic disease, leading to the development of irreversible cirrhosis(1-3). 肝炎的发生是高在中国(4-8)。 如果适当地对待在纤维变性阶段,肝病能被防止(9)。 然而,迄今没有有效的antifibrosis药物。 [translate] ...
Grade 3/4 TRAEs occurred in 3 patients (6.4%), including diarrhea, interstitial pneumonia, and hepatic impairment, respectively. Discontinuation of Afatinib was observed in only one participant due to grade 4 diarrhea. The most common TRAEs during NAT were diarrhea (78.7%), rash (78.7%), ...
A fragment originating from the cleavage of type VI collagen alpha3, namedendotrophin(measured by thenordicPRO-C6™ biomarker), has an important role for the progression of hepatic fibrosis,adipose tissue dysfunction, and insulin resistance. Monitoring the levels of these collagen fragments represent...
Metabolic characterization of the early stage of hepatic fibrosis in rat using GC-TOF/MS and multivariate data analysesMetabolic characterization of the early stage of hepatic fibrosis in rat using GC-TOF/MS and multivariate data analysesdoi:10.1002/bmc.3899The...
In order to further validate the feasibility of this new developed methodology, SPECT/CT imaging of normal C57BL/6 mice and hepatic fibrosis mice with known agent99mTc-GSA were also performed for comparison. Tissue analysis Paraformaldehyde-fixed samples were embedded in paraffin, cut into 5 μ...
1,3,16 Our data demonstrating that hepatic fibrosis stage is independently associated with liver-related events or death suggest that the degree of liver disease itself contributes to the excess morbidity and mortality observed in coinfected patients. Furthermore, these findings are consistent with ...
Relationship between alcohol use categories and noninvasive markers of advanced hepatic fibrosis in HIV-infected, chronic hepatitis C virus-infected, and u... It is unclear if the risk of liver disease associated with different levels of alcohol consumption is higher for patients infected with human...
HEPATIC fibrosisHEDGEHOG signaling proteinsMALARIAEOSINBackground/Aims: Malaria is the most deadly parasitic infection in the world, resulting in damage to various organs, including the liver, of the infected organism; however, the mechanism causing this damage in the liver remains unclear. Liver...
We would like to thank the staff of Division of Gastroenterology (Chulalongkorn University), Center of Excellence in Liver Diseases (KCMH), Research unit of hepatic fibrosis and cirrhosis (Chulalongkorn University) and Department of Radiology (Chulalongkorn University) for technical assistance and clinical...