FRAT1 expression and its correlation with pathologic grade, proliferation, and apoptosis in human astrocytomas FRAT1 was originally characterized as a protein frequently rearranged in advanced T-cell lymphoma, which inhibits GSK-3-mediated phosphorylation of β-cate... G Guo,B Liu,C Zhong,... -...
Furthermore, optic nerve tumours with a favourable prognosis were mainly classified as ‘pilocytic astrocytomas’ in 2000–09 whereas as ‘Gliomas, NOS’ in 2010–15 and were therefore increasingly considered to be malignant in the latter period (Hoogendijk R, personal communication). This study ...