(2007) SRY-related HMG box 9 regulates the expression of Col4a2 through transactivating its enhancer element in mesangial cells. Am. J. Pathol. 170, 1854 -1864Sumi E, Iehara N, Akiyama H, Matsubara T, Mima A, Kanamori H, Fukatsu A, Salant DJ, Kita T, Arai H, Doi T. SRY-...
SRY-related HMG-box gene 4) SOX4 A gene on chromosome 6p22.3 that encodes a member of the SOX (SRY-related HMG-box) family of transcription factors, which regulate embryonic development and determine cell fate. SOX4 may act as a transcription regulator after forming a complex with other ...
Stem cells have been discovered as key players in the genesis of different neoplasms including craniopharyngioma (CP), a rare tumour entity in the sellar region. Sox2 and Sox9 are well-known stem cell markers involved in pituitary development. In this st
Sox-2 Antibody,Sox2,Sox 2,SRY-box containing gene 2,sex determining region Y box-2,SRY related HMG box 2,Transcription factor SOX 2 供应商 Biovision 产品货号 3889-100 产品报价 ￥已停产 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-680...
Sry-related Box (简称Sox) 是一类含有一个HMG结构域的转录因子.HMG结构域结合DNA后使DNA发生弯曲从而达到调控遗传信息转录的效果.在器官分化期各个Sox成员在不同的细胞系中具有不同的转录调控功能,表明每种Sox转录因子具有其独特的与DNA相互作用的机理.研究每种Sox转录因子的HMG结构域与DNA结合前后空间结构变化可以为...
The Sox4 gene contains two important functional regions, namely, the SRY-related high-mobility-group (HMG) domain near the EMT in cancer The EMT refers to the morphological process in which epithelial cells are transformed into mesenchymal cells through specific procedures; this process plays an ...
SRY-related genes are known as Sox (Sry-box) genes. Two Sox cDNAs from Xenopus oocytes were analyzed. The deduced product of the Xenopus Sox gene (xSox-11) consisted of the standard domains of an HMG box, glycine/alanine-rich region and glutamic acid/aspartic acid-rich region and may be...
Sry-related box (Sox) transcription factors share a conserved high-mobility-group box domain (HMG-domain) that binds DNA in the minor groove and bends DNA for further assembly of transcriptional machineries. During organogenesis, each member of the Sox family triggers a specific cell lineage ...
SRY-related HMG box 9 regulates the expression of Col4a2 through transactivating its enhancer element in mesangial cells. Am J Pathol 2007; 170:1854-1864.Sumi, E., Iehara, N., Akiyama, H., Matsubara, T., Mima, A., Kanamori, H., Fukatsu, A., Salant, D. J., Kita, T., Arai...
The SRY gene on the human, mouse, and marsupial Y chromosomes is the testis-determining gene that initiates male development in mammals. The SRY protein has a DNA-binding domain (high mobility group or HMG box) similar to those found in the high-mobility-group proteins. SRY is specific for...