Here we review several potential mechanisms underlying the ER negative status of these breast cancers. The role of cross-talk between ER and Src-activated signal transduction as a mediator of both ER proteolysis and ER transactivation is discussed. Src kinase is often activated in breast cancer. ...
In several cases, loss of Src-family kinase activity results in activation of signaling, illuminating the fact that these molecules play important roles in inhibitory signaling. This review will focus on both the positive and negative roles these kinases play in immunoreceptor and integrin signaling ...
Abram, C. L., & Courtneidge, S. A. (2000). Src family tyrosine kinases and growth factor signaling.Exp Cell Res, 254, 1–13. ArticleCASPubMedGoogle Scholar Dey, A., She, H., Kim, L., et al. (2000). Colony-stimulating factor-1 receptor utilizes multiple signaling pathways to in...
Stop the Flow: A Paradigm for Cell Signaling Mediated by Reactive Oxygen Species in the Pulmonary Endothelium The lung endothelium is exposed to mechanical stimuli through shear stress arising from blood flow and responds to altered shear by activation of NADPH (NO... EA Browning,S Chatterjee,AB...
Interventions presented in this review promote an increase in contraceptive options and utilization, suitable for implementation in schools, healthcare settings, or community initiatives. The aims of this study encompass identifying the significant metrics for evaluating driver perception of vehicle stability...
or indirect regulation of related signaling pathways. In this review, we elucidate the role of SRC kinase in the regulation of glucose metabolism in cancer cells, and also discuss the research advance of SRC inhibitors, to explore the development o...
Src 及其信号通路在肿瘤发生过程中的作用
Cell. 2016;164:433–46. Article CAS PubMed PubMed Central Google Scholar Xie Y, Shi X, Sheng K, Han G, Li W, Zhao Q, et al. PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review). Mol Med Rep. 2019;19:783–91. CAS PubMed Google Scholar Mag...
REFERENCES Advanced Bladder Cancer (ABC) Meta-analysis Collaboration (2005) Neoadjuvant chemotherapy in invasive bladder cancer: update of a systematic review and meta-analysis of individual patient data advanced bladder cancer (ABC) meta-analysis collaboration. Eur Urol 48(2): 202 – 205 Blaveri E...
Younger animals ought to be excluded from immunological analyses as the existence of maternal antibodies within their systems may lead to a misinterpretation from the results. we review the serological methods found in WNV diagnosis and surveillance in Europe commonly. By examining previous and curr...