The spleen is a large, encapsulated, bean-shaped organ that is situated on the left side of the body below the diaphragm. The spleen contains T and B lymphocytes as well as many phagocytes and is a major component of the mononuclear phagocyte system. Although the structure resembles that of...
Molecular biology Structure and function relationship among the peptidyl prolyl cis/trans isomerases MISSISSIPPI STATE UNIVERSITY Nara Gavini ChaturvediVandanaThe spleen, made up of a capsule and trabeculae that enclose sinusoidal-rich pulp, sits at the crossroads between the vascular and reticulo...
TAIT, J. & CASHIN, N. F. (1925). Some points concerning the structure and function of the spleen. Quarterly Journal of Experimental Physiology 15, 421-445.Tait, J. , and M. F. Cashin 1925 Some points concerning the structure and function of the spleen . Q.J. Exp. Physiol. , 15...
, Steggerda, F. R., (1932), Observations on the structure and function of certain blood vessels in the spleen. The Journal of Physiology, 74 doi: 10.1113/jphysiol.1932.sp002852. Publication History Issue published online: 7 MAR 1932 Article first published online: 7 MAR 1932...
Distribution and function of non lymphoid cells positive for monoclonal antibody CVI-ChNL-68.2 in healthy chickens and those infected with Marek's disease virus Vet. Immunol. Immunopath. (1989) N. Van Rooijen Antigen processing and presentation in vivo: the microenvironment as a crucial factor Immun...
rupturing membranes of foreign cells (lysis); agglutination of antigen-bearing cells; and neutralization of viruses by altering their molecular structure, making them harmless. Other proteins promote inflammation, which helps prevent the spread of infectious agents. ...
Structure and function of the spleen. Nat. Rev. Immunol. 5, 606–616 (2005). Article CAS PubMed Google Scholar Tangye, S. G. & Good, K. L. Human IgM+CD27+ B cells: memory B cells or “memory” B cells? J. Immunol. 179, 13–19 (2007). Article CAS PubMed Google Scholar ...
DC modulation, and B cell modulation as well as their repositioning to deliver antibodies into the circulation[2,8]. Given this link between structure and function, compromise of splenic compartments leads to alterations in organ-specific and systemic immune responses in ways that are not yet fully...
The structure of the spleen is responsible for the various functions the organ performs in hematopoiesis, metabolism (for example, of iron), hemolysis, blood deposition and purification, and the protection of the body against injurious agents. The spleen acts as a biological filter for blood, from...
infection and generating immunological responses against pathogens—the spleen contributes significantly to the immune response. All things considered, the spleen’s intricate structure and various roles are central to the body’s capacity to sustain immunological function, blood composition, and overall ...