R. (2013). Synaptic connectivity between rat striatal spiny projection neurons in vivo: unexpected multiple somatic innervation in the context of overall sparse proximal connectivity. Basal Ganglia 3, 93-108. doi: 10.1016/j.baga.2013.04.001
Dynamic postnatal development of the cellular and circuit properties of striatal D1 and D2 spiny projection neuronsDynamic postnatal development of the cellular and circuit properties of striatal D1 and D2 spiny projection neuronsDENDRITIC spinesTHALAMIC...
This chapter describes medium spiny projection neurons (MSNs) as the principal cell type of the striatum. By stereological methods, they account for more than 95% of striatal neurons in the rat, and their total unilateral number in the rat brain is estimated as 2.8 million. The rema...
Decision letter: Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neurons A Kreitzer,J Trimmer - 《Elife》 被引量: 0发表: 2018年 Huntingtin Aggregate-Associated Axonal Degeneration is an Early Pathological Event in Huntington's Disease Mice Huntington's ...
Spiny Projection NeuronsTetanus Toxin Light ChainThe striatum collects and integrates information from many different areas of the brain and propels this forward to the basal ganglia (BG) output structures. In this way, the striatum is playing a pivotal role in control of voluntary movements and ...
This structure is pivotal in social behavior control, consisting mainly of spiny projection neurons (SPNs), distinguished by dopamine D1 or D2 receptor expression, connectivity, and associated behavioral functions. This study aims to examine how FMRP absence differentially affe...
These populations of direct and indirect pathway-projecting spiny projection neurons (SPNs) have classically been thought to promote or suppress actions, respectively, leading to a long-held hypothesis that increased output of direct relative to indirect pathway promotes compulsive behavior. Contrary to ...
The ventral striatum contains two populations of GABAergic spiny projection neurons, D1 and D2 SPNs, which differ with respect to both synaptic inputs and projection targets. To evaluate the role of MMP-1/PAR-1 signaling in the regulation of ventral striatal synaptic function, we performed ...
However, little is known about the spatial gene expression patterns and heterogeneity of spiny projection neurons (SPNs) within somatotopic subregions. Here, we show that the cell adhesion molecule gene Cdh20, which encodes a Type II cadherin, is expressed in discrete subregions covering the inner...
Galarraga E , Pacheco-Cano MT , Flores-Hernandez JV & Bargas J ( 1994 ). Subthreshold rectification in neostriatal spiny projection neurons . Exp Brain Res 100 , 239 – 249 .GALARRAGA, E., PACHECO-CANO, M.T., FLORES-HERNANDEZ, J. V., AND BARGAS, J. Subthreshold rectification in neo...