Research progress on cell therapy for spinal cord injury. This figure shows cell therapy clinical trials for SCI that are registered at ClinicalTrials.gov or have been published. This figure shows the timeline of cell therapy research for SCI and the number of clinical trials for different cells ...
Research progress on cell therapy for spinal cord injury. This figure shows cell therapy clinical trials for SCI that are registered at ClinicalTrials.gov or have been published. This figure shows the timeline of cell therapy research for SCI and the number of clinical trials for different cells ...
Chemokines such as CXCL-1, RANTES and MCP-1 are increasingly expressed after SCI to attract immune cells from blood to the lesion site, infiltrating the broken blood spinal cord barrier (BSCB) [27,28,29,30]. In mice models, neutrophils reach their peak at 24 h after SCI and subsequently ...
Changes in Cerebrospinal Fluid (CSF) parameters after AD-MSCs injection. AVEGF levels before and 2-weeks after infusion.BIL-15 levels before and 2-weeks after infusion.CIL12p40 levels before and 2-weeks after infusion.DIL-5 levels before and 2-weeks after infusion.EIL−7levels before and...
1J), indicating the efficient fusion of M2-Exos with PC12 cells. Evaluation of TPME biocompatibility Staining of NSCs for viability exhibited a substantial proportion of live cells (green) and a negligible fraction of dead cells (red) across all sample sets, indicating that TP and Exos did ...
b–e Incubation with dexamethasone (timeline in b) reduces neutrophil and macrophage numbers (c, d; Mann–Whitney U-test: **P < 0.01, ***P < 0.001), as well as the proportion of animals with axonal bridging (e; Fisher’s exact test: ***P < 0.001). f–i, Incubation ...
Figure 1. Experimental Timeline. 2.3. Single Pellet Grasping Training The SPG protocols and equipment were used as previously described [23]. Rats were first acclimatized to the SPG double-window enclosure and each rat’s preferred paw was established by manually counting the number of left and...
Intravenous Infusion of Adipose-Derived Stem/Stromal Cells Improves Functional Recovery of Rats with Spinal Cord Injury. Cytotherapy 2017, 19, 839–848. [Google Scholar] [CrossRef] Yin, T.-C.; Shao, P.-L.; Chen, K.-H.; Lin, K.-C.; Chiang, J.Y.; Sung, P.-H.; Wu, S.-C....