Single-cell RNA sequencing data can unveil the molecular diversity of cell types. Cell type atlases of the mouse spinal cord have been published in recent years but have not been integrated together. Here, we generate an atlas of spinal cell types based
Spinal substance P (Wilcoxon test; *p = 0.039) is significantly greater after collagenase injection than after injection of the vehicle (2 rats), but the same increase is not detected with pERK expression (Wilcoxon test; p = 0.147). Spinal cord images show regions of the superficial...
This is a dataset of 10,223 B-mode ultrasound images of porcine spinal cord before and after contracting an injury. The images were collected over 25 pigs at with varying aquisition parameters, such as spinal cord depth, imaging angle, gain, brightness, and ultrasound signal coupling medium. ...
slice/Users/julien/code/spinalcordtoolbox/python/envs/venv_sct/lib/python3.9/site-packages/scipy/ndimage/_measurements.py:1542: RuntimeWarning: invalid value encountered in scalar divideresults = [sum(input * grids[dir].astype(float), labels, index) / normalizerSuccessfully generated the QC resul...
Next-generation humanised mouse models and single-cell RNA sequencing (scRNAseq) approaches enable in-depth studies into human immune cell biology. Here we used NSG-SGM3 mice engrafted with human umbilical cord haematopoietic stem cells to investigate ho
Download: Download full-size image Fig. 1. Ependymal cells appear at mid-embryonic stage in the developing mouse spinal cord. (A) Representative coronal section images of YFP labeled ependymal cells around the central canal (dashed lines) of tamoxifen recombined FoxJ1-CreERT2::YFP. YFP expressio...
Spinal cord injuryDegenerative cervical myelopathy must be diagnosed with magnetic resonance imaging (MRI) which predicts spinal cord injury (SCI). The growing volume of medical imaging data can be managed by deep learning models, which provide a preliminary interpretation of images taken in basic ...
The mantle and marginal layers expand over time to become the grey and white matter in the mature spinal cord. (B) Organization of the spinal cord along the dorsal–ventral axis. The transverse section of E10.5 mouse spinal cord has been labeled with antibodies against Nkx6.1 (red), Olig2...
In this paper we also investigate how our approach can be used to detect spinal metastases, vertebral fractures and cord compression. Full size image Related work This work can be viewed as the follow-up to SpineNet, with several improvements over the initial version7. Firstly, the initial ...
The extent of spinal cord lesions was measured with an ImageJ software (National Institutes of Health, Bethesda, MD, USA) and expressed as the percentage of the lesioned area to the total area on the lesioned side. Quantification of CST fibers and terminal button-like swellings. For ...