The RNA sequencing data generated in this study have been deposited in the GEO database under accession number GSE186020. The key plasmids constructed in this study, their sequences, and maps have been deposited to Addgene (# 155305, # 155307). Source data are provided with this paper. Ref...
The scRNA sequencing data generated by this study has been deposited to GEO database under accession number: GSE218010. Processing and quality control of scRNA sequencing data Initial data demultiplexing, read alignment, UMI counting, and annotation of the raw read data were performed using the ...
The scRNA sequencing data generated by this study has been deposited to GEO database under accession number (GSE218010). The proteomics data generated have been deposited in proteomeXchange database under accession code PXD038152. The mRNA expression of CDK6, YAP1, and ERK2 in human HCC patients...
RNA-seq data discussed in this publication have been deposited in NCBI’s Gene Expression Omnibus (Edgar et al., 2002) and are accessible through GEO: GSE109827 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE109827). The accession number of metabolomics raw data reported in ...
Nat. Methods, 16 (2019), pp. 843-852, 10.1038/s41592-019-0509-5 View in ScopusGoogle Scholar 12 K. Lage Protein-protein interactions and genetic diseases: the interactome Biochim. Biophys. Acta, 1842 (2014), pp. 1971-1980, 10.1016/j.bbadis.2014.05.028 View PDFView articleView in Scopu...
Scn1a encodes the voltage-gated sodium channel alpha subunit. De novo null mutations in SCN1A result in severe myoclonic epilepsy of infancy [50]. SCN1A mutations have been associated to a number of neurological disorders, including generalized epilepsy with febrile seizures plus, Dravet syndrome,...
Copy number variation FDR: False discovery rate GEO: Gene Expression Omnibus GMT: Gene matrix transposed IBD: Inflammatory bowel disease IFN: Interferon IN: interleukin KEGG: Kyoto Encyclopedia of Genes and Genomes MSigDB: Molecular Signatures Database ...
(FDR) <7%), MAT score >0, minimum number of probes for each region >10, and average length for the ChIP fragment >600 bp were used as the peak detection parameters in this discovery phase of high-throughput screening for potential RORA targets. The microarray data from this study have ...
(GEO) database. Differential methylation of LINE-1 andAluelements was examined in a total, locus- and subfamily-specific manner for each ASD variant, including heterogeneous ASD (n = 52), ASD with 16p11.2 del (n = 7), and ASD withCHD8variants (n = 15). Biological ...
2f). GSTM1 and NNAT were previously suggested to be involved in inflammation25,26. We also observed an increased mRNA expression of the SCZ-risk gene complement factor C4A (Fig. 2g), a further regulator of the innate immune response, which is in agreement with mRNA quantifications performed...