Organ-specific autoimmune disorders constitute a group of conditions where the immune system mistakenly targets and attacks specific organs within the body. This chapter delves into the intricate mechanisms and diverse manifestations characterizing these disorders. Focusing on organ-specificity, it explores ...
The development of therapeutic approaches for the induction of robust, long-lasting and antigen-specific immune tolerance remains an important unmet clinical need for the management of autoimmunity, allergy, organ transplantation and gene therapy. Recent breakthroughs in our understanding of immune tolerance...
however, can also lead to the generation of carbohydrate-specific antibodies that cross-react with human antigens, thereby contributing to the development of autoimmune disorders.
Subjects had no history of heart disease, COPD, malignancy, or other systemic disorders that would be exclusionary, as clarified by Reeves et al. (2003) [31]. Importantly, care was taken to assess female subjects at the same phase of the menstrual cycle, namely in the follicular phase. ...
Immunotherapyuseschemicals, either natural or synthetic to enhance your own immune system to fight or control the cancer cells. breastcancersingapore.com breastcancersingapore.com 免疫治疗采用自然或人工合成的化学物质来加强病人的免疫系统,以对付或控 制癌细胞。
Disorders of the Human immune system Defects Hay fever Transplant rejection Autoimmunity Infection carriers Hypersensitivity Rx that lead to tissue damage Occur when person is sensitized 4 types Autoimmune disease From loss of self tolerance Self tolerance occurs during fetal development Clonal deletion Clon...
functional bowel disorders diet symptom severity secretion nucleosides bile acids short chain fatty acids Introduction Irritable bowel syndrome (IBS) is a globally prevalent disorder characterized by recurrent abdominal pain or discomfort. IBS is predominantly seen in females and is associated with changes ...
We then discuss the physiological and pathological consequences of a regionally distinct immune system in a single organ, but also discuss where our insight into the role of the compartment for disease development is still very limited. Finally, we discuss the technological and therapeutic implications...
Interestingly, while the regulatory target genes in the brain tend to enrich in nervous system development related processes, those in the non-brain tissues are inclined to interfere with synapse and neuroinflammation related processes. Compared to psychiatric disorders, neurological disorders present more...
(2) immune system disorders, (3) epithelial cell repair (skin, lung and/or intestinal epithelia), (4) hematopoiesis, and/or (5) disorders caused by various physical and/or mental stresses. For example, transgenic mammals or cell lines containing the transgene for IL-8 will be useful for ...