we performed single-cell transcriptome sequencing onplk1-depleted planarian samples at 5 dpa during regeneration (Fig.6a). After initial quality control, we acquired single-cell transcriptomes of a total of 7941 cells from theplk1RNAi sample and characterized the cell types using the single cell dat...
Cui et al. present a comprehensive three-dimensional spatiotemporal transcriptome landscape of planarian regeneration. They identified a novel pluripotent neoblast subtype and new spatially specific genes essential to tissue regeneration.doi:10.1038/s41467-023-39016-0Cui, Guanshen...
G. A single cell transcriptome atlas of the developing zebrafish hindbrain. Development 147, dev184143 (2020). Delile, J. et al. Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord. Development 146, dev173807 (2019). Lohoff, ...
中国科学家解码人脑多区域时空发育奥秘上篇 | 2023年12月,中国科学院动物研究所焦建伟团队、广州国家实验室董骥团队、北京大学杜鹏团队和北京大学靳蕾团队在Cell(IF=64.5)发表题为Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain的文章。通过单细胞(scRNA-seq)和时空转...
spatial cleavage under targets and tagmentation (CUT&Tag) technology [156,157], which is the main focus of this paper; the other relying on high-resolution imaging techniques, such as multifluorescence in situ hybridization. Presently, spatial epigenomics primarily concentrates on transcriptome and ...
multiplexed error-robust fluorescence in situ hybridization; MIBI-ToF, multiplexed ion beam imaging by time of flight; MS, mass spectrometry; MSI, mass spectrometry imaging; OT, Orbitrap; scRNA-seq, single-cell transcriptome sequencing; SIMS, secondary ion mass spectrometry; sST, sequencing-based spa...
Spatio-temporal transcriptome of the human brain. Nature ... J Fernandez-Irigoyen,A Labarga,A Zabaleta,... - 《Proteomics Clin Appl》 被引量: 1发表: 2015年 STAB: a spatio-temporal cell atlas of the human brain The human brain is the most complex organ consisting of billions of neuronal...
multiplexed error-robust fluorescence in situ hybridization; MIBI-ToF, multiplexed ion beam imaging by time of flight; MS, mass spectrometry; MSI, mass spectrometry imaging; OT, Orbitrap; scRNA-seq, single-cell transcriptome sequencing; SIMS, secondary ion mass spectrometry; sST, sequencing-based spa...
(A) UMAP plot of spot transcriptome clusters from each slide shown on left; clusters are visualized on tissue covered slide areas (left center). Integration with scRNA-Seq cell type annotations are shown on the right, with tissue morphology of the region shown right center for 12 PCW TI (i...
are as follows: (1) explore transcriptome-wide spatiotemporal patterns in the three hearts by ST, (2) dissect cell type heterogeneity of the heart at intermediate time point by scRNA-seq, (3) target key genes at subcellular resolution by ISS, and (4) generate 3D gene expression atlas. ...