ResourceSpatiotemporal analysis of human intestinal development at single-cell resolution Author links open overlay panelDavid Fawkner-Corbett 1 2 3 8, Agne Antanaviciute 1 4 8, Kaushal Parikh 1 2 8, Marta Jagielowicz 1 2, Ana Sousa Gerós 1 2, Tarun Gupta 1 2, Neil Ashley 5, Doran ...
CD27−IgM+IgD+CD45RB+marginal zone precursor B cells emerge from the naïve B cell pool. Analysis of B cells in GALT (n = 8); tonsil (n = 5), spleen (n = 6).aZ-score outcomes of a permutation test to determine if cell subpopulations significantly neighbour each othe...
Spatial and temporal analysis of the stomach and small-intestinal microbiota in fasted healthy humans. mSphere. 2019;4(2):4. doi:10.1128/mSphere.00126-19. (Open in a new window)Web of Science ®(Open in a new window)Google Scholar...
Over 150years ago, methods for quantitative analysis of gastrointestinal motor patterns first appeared. Graphic representations of physiological variables were recorded with the kymograph after the mid-1800s. Changes in force or length of intestinal muscles could be quantified, however most recordings ...
In addition, no comprehensive analysis of the local coordination of the various immune compartments, nor of the genome plasticity of cancer cells, has been conducted in the same patients. To gain deeper insights into tumor progression and tumor recurrence mechanisms in human colorectal cancer (CRC)...
et al. Spatiotemporal analysis of human intestinal development at single-cell resolution. Cell 184, 810–26 e823 (2021). Article CAS PubMed PubMed Central Google Scholar Asp, M. et al. A spatiotemporal organ-wide gene expression and cell Atlas of the developing human heart, cell. Cell ...
A significant fraction of sudden death in children and young adults is due to viral myocarditis, an inflammatory disease of the heart. In this study, by using integrated single-cell and spatial transcriptomics, we created a high-resolution, spatially res
Data on molecules of TJs and GJs from the Human Genome Organization (HUGO) portal are summarized in Table S2 [26]. Furthermore, clustering analysis was performed on the expression profiles of 47 molecules to identify CC phenotypes that are linked to CRC and stratify CRC patients. Moreover, th...
Fig. 1: Study strategy and ILC-related populations analysis overview. aSchematic overview of the strategy of this study. Cells from human fetal hematopoietic (liver), lymphoid (thymus and spleen) and non-lymphoid (intestine, skin and lung) tissues at indicated gestational stages were first labeled...
Intestinal infectious diseases (IIDs) can impact the growth and development of children and weaken adults. This study aimed to establish a spatial panel model to analyze the relationship between factors such as population, economy and health resources, a