The SOUL, or heme-binding protein HBP/SOUL, family represents a group of evolutionary conserved putative heme-binding proteins that contains a number of members in animal, plant and bacterial species. The structures of the murine form of HEBP1, or p22HBP, and the human form of HEBP2, or ...
Structure SOUL/HBP Hemebinding ProteinsMurine p22HBP, a 22-kDa monomer originally identified as a cytosolic heme-binding protein ubiquitously expressed in various tissues, has 27% sequence identity to murine SOUL, a heme-binding hexamer specifically expressed in the retina. In contrast to murine ...
Szigeti A, Bellyei S, Gasz B, Boronkai A, Hocsak E, Minik O, Bognar Z, Varbiro G, Sumegi B, Gallyas F Jr (2006) Induction of necrotic cell death and mitochondrial permeabilization by heme binding protein 2/SOUL. FEBS Lett 580(27):6447-6454....
2013. The heme-binding protein SOUL3 of Chlamydomonas rein- hardtii influences size and position of the eyespot. Mol. Plant 6:931-944.Schulze T, Schreiber S, Iliev D, Boesger J, Trippens J, Kreimer G, Mittag M (2013) The heme-binding protein SOUL3 of Chlamy- domonas reinhardtii ...
HemeproteinsAmino Acid SequenceMurine p22HBP, a 22-kDa monomer originally identified as a cytosolic heme-binding protein ubiquitously expressed in various tissues, has 27% sequence identity to murine SOUL, a heme-binding hexamer specifically expressed in the retina. In contrast to murine SOUL, which...
Iliev et al., "The heme-binding protein SOUL3 of Chlamydomonas reinhardtii influences size and position of the eyespot," Molecular Plant. In press.Schulze T, Schreiber S, Iliev D, et al. The heme-binding protein SOUL3 of Chlamydomonas reinhardtii influences size and position of the eyespot. ...
Heme binding proteinIronTetrapyrrole metabolismEmbryonic developmentSOUL/p22HBP familyPineal glandYolk syncytial layerPronephrosThe SOUL/p22HBP family is an evolutionarily ancient group of heme binding proteins with a main function as cytosolic buffer against tetrapyrrole accumulation. Structural and biochemical ...
Protein crystalsProtein SOULSecondary structureRaman spectroscopyDFT computationProtein SOUL is a new member of the recently discovered putative heme-binding protein family called SOUL/HEBP and, to date, no structural information exists for this protein. Here, micro-Raman spectroscopy is used to study ...
Discovery of a putative heme-binding protein family (SOUL/HBP) by two-tissue suppression subtractive hybridization and database searches. Brain Res. Mol. 1999, 74, 175–181. [CrossRef] 2. Fortunato, A.E.; Sordino, P.; Andreakis, N. Evolution of the SOUL heme-binding protein superfamily...