Side Effects, Sotalol HClConcise Info
Sotalol hydrochloride/Sotalol hydrochloride AF tablets: Initial dosage in adults is 80 mg twice daily. Increase the dose as needed in increments of 80 mg/day, every 3 days to a maximum 320 mg total daily dose (2.2) Pediatrics: Dosage depends on age (2.4) Dosage Forms and Strengths Sotalol...
Because of d,l-sotalol–related side effects, 17 patients (4.3%) did not undergo repeat programmed electrical stimulation. d,l-Sotalol, at a mean daily dose of 465 ± 90 mg, prevented the induction of sustained VT/VF in 151 patients (38.1%). In 119 patients (30.1%), <10 repetitive ...
Conclusion: Initiating sotalol at 120鈥 160 mg orally twice per day marginally increases the risk of cardiac and non-cardiac side effects compared to the standard starting regimen of 80 mg b.i.d. Such an accelerated dosing regimen neither shortened hospitalization nor had any effect on treatment...
CONCLUSION: Initiating sotalol at 120-160 mg orally twice per day marginally increases the risk of cardiac and non-cardiac side effects compared to the standard starting regimen of 80 mg b.i.d. Such an accelerated dosing regimen neither shortened hospitalization nor had any effect on treatment ...
The authors concluded that amiodarone may be more effective but that it also has more side effects than sotalol. They did not consider the cost of the 2 drugs. According to our hospital pharmacy, the cost of amiodarone, 200mg/day, is approximately US $8.10. Sotalol, 160 mg (80 mg twice...