Twitter Google Share on Facebook Medical Wikipedia so·ta·lol (sō′tə-lôl′, -lōl′) n. A beta-blocker drug, C12H20N2O3S, used in its hydrochloride form to treat certain cardiac arrhythmias. [Alteration ofsorta(because sotalol is only "sort of" a beta-blocker, since it also ha...
These patients received 40 mg of sotalol orally twice daily from the first post-operative day for 6 weeks and 2 g of magnesium intravenously immediately post surgery and on the first post-operative day. We developed a propensity score for the probability of receiving sotalol and magnesium after ...
In rabbits, a high dose of Sotalol HCl (160 mg/kg/day) at 16 times the MRHD as mg/kg (6 times the MRHD as mg/m2) produced a slight increase in fetal death likely due to maternal toxicity. Eight times the maximum dose (80 mg/kg/day or 3 times the MRHD as mg/m2) did not...
Sotalol, 160 mg (80 mg twice/d), is approximately $9.70 a day; with titration of sotalol up to 3 times to 480 mg/day, the cost would be over $28/day, substantially more than the cost of amiodarone. Clinically, the greater effectiveness of amiodarone and its lower cost favour its use...
Methods. Two hundred seven consecutive coronary artery bypass patients (mean age 62 卤 11 years) were randomized to receive sotalol alone (80 mg twice daily for 5 days starting from the morning of the first postoperative day) (group S), magnesium alone (1.5 g daily for 6 days starting in...
Patients with ejection fraction <40% or clinically significant heart disease were excluded. Patients randomized to amiodarone began with 800 to 1,600 mg/day for 7 to 14 days orally. After the initial loading phase, the drug dose was tapered to maintenance levels over 7 to 12 days; thereafter...
In deeply anesthetized rats (injected 40 mg/kg thiopental (Rotexmedica, Trittau, Germany) and 10 mg/kg diazepam (Apaurin; Krka, Slovenia) intraperitoneally), complete calvariectomy was performed, and to induce rapid vascular failure and concomitant general syndrome, we applied intragastrically sotalo...