偶联反应(Cross-coupling reaction)是一类重要的有机合成反应,是通过两个或多个有机分子之间的键合并形成新的有机分子。这个过程发生在两个底物分子之间,一般在有机金属化合物的催化下进行。偶联反应具有高效性、高选择性和广泛适用性的特点,因此在药物合成和材料科学等领域起着重要的作用。 为什么要进行偶联反应? 偶...
Sonogashira–Hagihara Coupling towards Diaryl Alkynes Catalyzed by FeCl3?6?H2O/Cationic 2,2’‐Bipyridyl[J] . Tzu‐TingHung,Chun‐MinHuang,Fu‐YuTsai.ChemCatChem . 2012 (4)Sonogashira-Hagihara Coupling towards Diaryl Alkynes Catalyzed by FeC13.6 H2O/Cationic 2,2’’-Bipyridyl. T. T. Hung,C. ...
Inthispaper,porousaromaticmatrixmaterialswerepreparedbySonogashira-Hagiharacouplingreactionbetweentri-acetylenylbenzene(4-acetylenylbenzene)amine,atri-conicalconstructionunit,andatwo-nodelinearbridgedsegmentP-TABB. Afterthepreparationofthetargetmaterial,thepreparedporousaromaticmatrixmaterialwillbecharacterizedbyinfraredsp...
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CheminformSynthesis of Unsymmetrical Diarylethynes by Pd(0)/Cu(I)-cocatalyzed Sila-Sonogashira-Hagihara Coupling Reactions of Alkynylsilanes with Aryl Tosylates or Mesylates. Yasushi Nishihara,Daisuke Ogawa,Shintaro Noyori. Chemistry Letters . 2012...
A dithienotitanacyclopentadiene-containing π-conjugated polymer was obtained in 53% yield by the Pd/Cu-catalyzed Sonogashira-Hagihara cross-coupling polycondensation of a diiododithienotitanacyclopentadiene derivative with 1,4-dioctyloxy-2,5-diethynylbenzene. The resulting polymer is soluble in organic ...
Sonogashira-hagihara cross-coupling reactionThe synthesis and transformations of a π-conjugated tellurophene-containing polymer are described. A π-conjugated tellurophene-containing polymer was obtained in 56% yield by the Sonogashira-Hagihara cross-coupling polycondensation of 2,5-di(4-bromophenyl)...
以往Sonogashira-Hagihara反應需要加入一價銅當共催化劑,而在此系統中不需要加入銅,我們利用加入Zn幫助產物的生成,即可合成出Csp2-Csp cross-coupling的產物都有不錯的產率.再者利用1-aryl-3-methyl-1-butyn-3-ol做為terminal alkynes的來源,達到one-pot反應效果,不需再多一個分離與純化的步驟,可以減少有機溶液的...
The complex was a highly efficient catalyst for the Sonogashira- Hagihara coupling reaction in the absence of a copper cocatalyst and an amine base under aerobic condition. This protocol can be applied for different aryl halides including chloroarenes. The catalyst can be reused several times ...
ChemInform Abstract: Mechanistic Insights into Copper-Catalyzed Sonogashira-Hagihara-Type Cross-Coupling Reactions: Sub-Mol% Catalyst Loadings and Ligand Effects.polyphenylalkyne derivatives (tolan derivatives)C-C bond formationcatalysis, phase-transfer catalysis...