Plasma Sodium Correction Rates in Patients with Severe Hyponatremia Treated with Hypertonic Saline with and without Desmopressindoi:10.1681/ASN.2024sryz1wamZain AlShanablehUPMC, Pittsburgh, Pennsylvania, United States;Anna RalchenkoUPMC, Pittsburgh, Pennsylvania, United States;Jonathan Guerrero Yabes...
Central pontine myelinolysis (CPM) is a serious demyelination disease commonly associated with the rapid correction of hyponatremia. Although its pathogene... Y Sugimura,T Murase,S Takefuji,... - 《Experimental Neurology》 被引量: 267发表: 2005年 Increased osmolarity and cell clustering preserve ca...
the brain returns to its normal size. It is these adaptive changes that make the brain susceptible to damage during too‐rapid correction of the hyponatremia. Rapid correction of hyponatremia can cause neuronalinjury, possibly leading toosmotic demyelination syndromeorcentral pontine myelinolysis, a pote...
Rapid correction of hyponatremia is potentially dangerous with risk of serious neurologic complications. Brain adaptations reducing risk of cerebral edema make the brain vulnerable to injury when chronic hyponatremia is too rapidly corrected, which is known as osmotic demyelination syndrome (ODS). To avoi...
hyponatremia is the most frequent electrolyte abnormality observed in hospitalized subjects. It is constantly associated with an increased risk of complications and reduced survival in patients. However, the rapid correction by hypertonic sodium solution infusion even produced more neurological dramatic compli...
However, the rapid correction by hypertonic sodium solution infusion even produced more neurological dramatic complications2. Thus, knowing the brain components involved in sodium appetite (SA) onset, and the temporal course of their interplay during hyponatremia, becomes highly relevant. Sodium appetite...
Hyponatremia: evaluating the correction factor for hyperglycemia PURPOSE: There are no controlled experimental data that assess the accuracy of the commonly used correction factor of a 1.6 meq/L decrease in serum sodium ... Teresa,A.,Hillier,... - 《American Journal of Medicine》 被引量: 656发...
products in patients with no prior history of seizures. The seizure cases were associated with electrolyte abnormalities (e.g., hyponatremia, hypokalemia, hypocalcemia, and hypomagnesemia) and low serum osmolality. The neurologic abnormalities resolved with correction of fluid and electrolyte abnormalities....
but at a rate not exceeding 0.8 mEq/kg/hr. Symptoms are not reliable for clinical management because they are not often apparent until serum sodium levels fall to less than 120 mmol/L, and their severity is directly related to the rapidity of onset and magnitude of hyponatremia. If not pro...
For patients with renal disease, hyponatremia at baseline and time-dependent hyponatremia or hypernatremia had higher risk of mortality. Dysnatremia may be a potential target for correction for clinicians. However, whether correct dysnatraemia could improve outcomes should be evaluated in future studie...