Molecular heterosis may be present in 50% of all of the gene associations,44 and it has also been reported for variations in the PARP-1 gene.32,34 The biological meaning of the 'protective' effect of the heterozygous genotype of rs1136410 toward HT cannot be easily explained by the ...
Vasil M: Pseudomonas aeruginosa: biology, mechanisms of virulence, epidemiology. J Pediatr. 1986, 108: 800-805. 10.1016/S0022-3476(86)80748-X. Article CAS PubMed Google Scholar El Solh AA, Akinnusi ME, Wiener-Kronish JP, Lynch SV, Pineda LA, Szarpa K: Persistent infection with Pseudom...
genome-wide SNPs and phenotype dementia from two large population-based studies.Application of deep learning methods using GWAS SNPs to predict dementia in population-based studies.Ability to infer biological meaning from latent embedding of high dimensional omics to understand the new biology in AD/...
meaning that only a few of the individuals carrying them will develop disease. However, because such polymorphisms are likely to be very common in the population, they make a significant contribution to the health burden of the population. Examples of common polymorphisms associated with an increased...
D. Laufer, "MicroRNA-mediated regulation of gene expression is affected by disease-associated SNPs within the 3-UTR via altered RNA structure," RNA Biology, vol. 9, no. 6, pp. 924-937, 2012.Haas U, Sczakiel G, Laufer SD. MicroRNA- mediated regulation of gene expression is af- ...