Full size table Biological Pathways Twelve of the 14 biological pathways detected in our analysis (Table 4) have already been linked in the literature, either explicitly or indirectly, to the alcoholism. Two pathways have been explicitly cited for their involvement in the development of alcohol dep...
Full size image Because of the length of the RRL fragments (~110-130 bp), there is an overlap between paired forward and reverse reads (62 nucleotides each) from position 48 onwards. This overlap results in a higher sequence depth and a tiny increase in the number of SNPs being detected ...
Journals & Books Help Search My accountSign in View PDF Download full issue Search ScienceDirect Outline Main Text Declaration of Interests ReferencesCited by (3)Figures (1)Cell Volume 174, Issue 3, 26 July 2018, Pages 501-502PreviewChanging the Guard at a Prostate Cancer SNP ...
Full size image Two genome builds were tested to estimate biases in QPX transcriptome contig assemblies and compare parameters used for each build. Both builds and one transcriptome were specific to the MA QPX strain [11]. Two other transcriptomes were specific to a NY QPX strain, both assembled...
Full size table TARP γ-8 knockout mice exhibit increased aggression and impulsivity To understand the causal relationship between the decrease of TARP γ-8 and ASPD, we designed systematic neurobehavioral tests and analyzed the behavior of γ-8−/−and γ-8+/−mice27, in which either bot...
Pregnenolone Biosynthesis” (P = 1.91E-02). The top IPA computed networks showed that the genes in the networks were associated with “Cell Morphology, Cellular Function and Maintenance, Carbohydrate Metabolism” and “Immunological Disease, Inflammatory Disease, Inflammatory Response”. The full ...
Full size image SNP detection Two criteria are important for selecting SNPs for an Infinium genotyping array. First, the target SNP should have a high probability (i.e., low P-value,PS) of being a true variant. Second, the target SNP should have no variants in its flanking sequences wher...
Full size image The net nucleotide distance between the groups is shown in Table S2, and the maximum distance was recorded between GP1 and GP2 (0.003). The genetic distance between GP1 and GP3 (0.0026) was closely related to the distance between GP2 and GP3 (0.0025). The results from Str...
Full size image Discussion In this work, we report the first SNPlex genotyping system application in higher plants, which allowed the development of markers anchoring the grapevine genome. To date, a few low- and mid-throughput methods based on SSCP and minisequencing assay have been used for ...
Full size image Segregation distortion was observed in all four mapping populations, being most pronounced in the MxB population in the pericentric regions of 1H, 2H, 5H and 7H and the long arm of 7H. Interestingly, on 7H the distortion was toward the maternal allele (Morex) in the pericen...