2g). Similarly, full-length coverage with Smart-seq3xpress resulted in significantly (2–5-fold) increased read support over exon–exon and exon–intron splice junctions, which form the basis for RNA velocity inference16 (Fig. 2h). To perform a direct comparison of cluster granularity, we ...
According to the half r2 value of the six breeds, we considered 10 kb as the SNP site-linked distance for the signal detection window. Genome-wide selective signature detection To better mine the functional areas closely related to egg-laying traits, we assigned three breeds (HY, ZE, SC, ...
Between 21 and 28 days after conception, the neural plate folds and closes to form the neural tube; this structure later develops into the brain and spinal cord. Failure of the neural tube to close most commonly leads to spina bifida or anencephaly, although encephalocele, craniorachischisis...
The correlation of the minor allele count and observed minor allele frequency in the SNP discovery pool was 0.72. Conclusion We identified almost 150,000 SNPs in wild mallards that will likely yield good results in genotyping. Of these, ~101,000 SNPs were detected within our wild mallard ...
The development of the cortex is a delicate balance between proliferation, differentiation, and migration of neural progenitors (NPs). Throughout developmental process, various cellular mechanisms ensure that NPs differentiate into the correct cell subtypes, migrate to their correct regions, and form the...
A recent publication documented the somatic NRF2 gain-of-function mutations in cancer [112]. However, mutation of either Keap1 and NRF2 in RCC is a very rare event (Supplemental TableS2) and the mutant cohorts were too small to form meaningful evaluation of the role of their mutations in RC...
Dense single nucleotide polymorphism (SNP) genotyping arrays provide extensive information on polymorphic variation across the genome of species of interest. Such information can be used in studies of the genetic architecture of quantitative traits and t
This structure is the source of pluripotent cells. Pluripotent stem cells (PSCs) form cells of all germ layers but not extraembryonic structures, such as the placenta. Embryonic stem cells (ESCs) are an example. ESCs are derived from the inner cell mass of preimplantation embryos. Another ...
The first step of data analysis is to assess and clean the raw sequencing data, which is usually provided in the form of FASTQ files [32]. Quality control visually reflects the quality of the sequencing and purposefully discards low-quality reads, eliminates poor-quality bases and trims adaptor...
In accordance with these findings, in another study, the abscission layer started to form at 12 h after a treatment with 400 mg/L ethylene treatment of cotton bolls [51]. However, some studies have shown that although ethylene can accelerate abscission under many conditions, it is not ...