To conclude, the study demonstrated a perceptible association between the SNP E298D and NOS3 protein structure stability that appears to have a bearing on the enzyme's function with a deleterious role in EH.Sharma, KavitaDepartment of Biotechnology, Jamia Millia Islamia, New Delhi, IndiaHema, ...
SNPprotein structurebioinformaticsMutations affecting amino acids at protein–protein interfaces can lead to disease.There are numerous mechanisms by which these ... CM Yates,MJ Sternberg - 《Journal of Molecular Biology》 被引量: 175发表: 2013年 Structure shows glycosaminoglycan- and protein-recognition...
[16] C Ferrer - Costa,M Orozco and X de Ia Cruz. Characterization of disease - associated singIe amino acid poIymorphisms in terms of se uence and structure properties [J]. J. MoI. BioI, 2002,315(4):771 - 786. [17] Z Wang and J MouIt. SNPs, protein structure, and ...
We incorporate functional predictions of protein structure, gene regulation, splicing and miRNA binding, and consider whether the alternative alleles of a SNP are likely to have differential effects on function. Users can assign weights for different functional categories of SNPs to further tailor SNP ...
snp Star Here are 114 public repositories matching this topic... Language: All Sort: Most stars ncbi / icn3d Star 151 Code Issues Pull requests web-based protein structure viewer and analysis tool interactively or in batch mode nodejs delphi webgl vr ar jupyter-notebook chemical protein snp...
SNPs need to cause the change of amino acid first, and then a slightly change in amino acid will trigger a sharp change in the structure of protein. Here is a picture to briefly explain the genetic process inside our body that start from DNA and you can image what will happen if the ...
Two functional polymorphisms (rs3752233 and rs3752246) were identified on the basis of less protein stability, a low likelihood of mutability, a changing of protein structure and function. Interestingly, a completed LD between rs3752233 (R463H) and rs4147918 (Q1686R) was detected in Utah ...
SNP关联分析与复杂疾病 SNP association study and complex diseases 口腔病理研究室 Department of Ora 1 Path ology School of Stoma to logy P
The β-casein is the most abundant protein in camel Pauciullo,A.,Erhardt,... - 《Gene An International Journal Focusing on Gene Cloning & Gene Structure & Function》 被引量: 21发表: 2014年 Knock out of bovine beta casein gene by homologous recombination利用Red同源重组系统进行牛β酪蛋白基因...
Description : A web-based suite of tools to predict and analyze protein structure, function and mutations. It has advanced remote homology detection methods to build 3D models, predict ligand binding sites and analyze the effect of amino acid variants, e.g., non-synonymous SNPs. pibase Descript...