Signal transduction Neuro science Product No.RPB222Hu01 Organism SpeciesHomo sapiens (Human)Same name, Different species. SourceProkaryotic expression HostE.coli Endotoxin Level<1.0EU per 1µg (determined by the LAL method) Subcellular LocationMembrane, Nucleus, Cytoplasm ...
The Thy1SNCA/15 mice overexpress 1–2 copies of the gene encoding human wild-type αSyn that is driven by the mouse thymus cell antigen 1 (Thy1) promoter leading to neuronal expression of αSyn in the brain and gut [7, 8, 60]. Thy1SNCA/15 mice were first described by Choi et al...
The Thy1SNCA/15 mice overexpress 1–2 copies of the gene encoding human wild-type αSyn that 13 Acta Neuropathologica (2022) 143:55–73 57 is driven by the mouse thymus cell antigen 1 (Thy1) pro- moter leading to neuronal expression of αSyn in the brain and gut [7, 8, 60]. ...
In our work, we used a new technology for multiplex profiling of gene expression using barcoding on the Nanostring platform to assess the activity of mitochondrial genes on iPSC-derived cultures of dopaminergic neurons obtained from patients with LRRK2- and SNCA-associated genetic forms PD and a...
In our work, we used a new technology for multiplex profiling of gene expression using barcoding on the Nanostring platform to assess the activity of mitochondrial genes on iPSC-derived cultures of dopaminergic neurons obtained from patients with LRRK2- and SNCA-associated genetic forms PD and a...