Therefore, it becomes easy for the nucleophile to attack the alkyl halides and result in the substitution. On the other hand, it is tough to break C-F bond because it is very strong and in turn, it is difficult for the nucleophile to attack. The reactivity order of alkyl halides in...
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“big barrier” to the SN1 reaction as beingcarbocation stability, That is, any factor which leads to the increased stability of a carbocation intermediate will increase the rate of the SN1. That’s why this pathway tends to be favored by tertiary alkyl halides, since the order of ...
Primary Alkyl Halides Reactivity of R-X with nucleophiles Unhindered primary R-X S N 2 with good nucleophiles that are not strongly basic S N 2 with good nucleophile that are also strongly basic E2 with nucleophiles that are strongly basic and hindered ...