This order differs significantly from that observed for the double SN2 displacement reaction of nucleophiles with compounds of the type NH2-X. This appears to be the first report of differing orders of nucleophilicities of bases involved in SN1 and SN2 reactions at electron-deficient nitrogen ...
Rank A, B, and C in order of increasing SN2 reactivity. Rank A, B, and C in order of increasing SN1 reactivity. Rank the below compounds in order of increasing reactivity in nucleophilic acyl substitution. Rank the following compounds in order of increasing reactivity toward nucleophi...
In deuteriochloroform these intermediates decompose by a first-order process which involves rate-determining collapse of the phosphonium halide ion-pair with SN2-type fission of the alkyl–oxygen bond. Rates for chloride, bromide, and iodide are similar. In a more ionising medium (deuterio...
This result suggests that the Lewis acid catalyzes the acetalization reaction to proceed by a stepwise SN1-like mechanism (Scheme 2). A Lewis acid induces a catalytic C–O bond cleavage of the epoxy ring to generate a carbocation on the carbon atom of the fullerene moiety. This is followed...
molecules Article A Computational Study of Structure and Reactivity of N-Substitued-4-Piperidones Curcumin Analogues and Their Radical Anions Maximiliano Martínez-Cifuentes 1,*, Boris Weiss-López 2 and Ramiro Araya-Maturana 3,* 1 Programa Institucional de Fomento a la Investigación, Desarrollo e...
1. Introduction Hydrogenases (H2ases) are a class of biological enzymes that catalyze the reversible interconversion of H2 2H+ + 2e− in various microorganisms such as bacteria, archaea, and some eukaryotes [1–3]. According to the metal composition in their active site, H2ases are generally...
Article Unveiling the Unexpected Reactivity of Electrophilic Diazoalkanes in [3+2] Cycloaddition Reactions within Molecular Electron Density Theory Luis R. Domingo 1,* , Mar Ríos-Gutiérrez 1 and Nivedita Acharjee 2 1 Department of Organic Chemistry, University of Valencia, Dr. Moliner 50, ...