NIHSS Scores in Ischemic Small Vessel Disease: A Study in CADASIL Background: The National Institutes of Health Stroke Scale (NIHSS) is widely used to measure neurological deficits, evaluate the effectiveness of treatment... M Yao,D Hervé,N Allili,... - 《Cerebrovascular Diseases》 被引量: ...
Cerebral small vessel disease (SVD) is a frequent finding on CT and MRI scans of elderly people and is related to vascular risk factors and cognitive and motor impairment, ultimately leading to dementia or parkinsonism in some. In general, the relations are weak, and not all subjects with SVD...
Cerebral small vessel disease (CSVD) accounts for nearly 20% of all ischemic strokes and is associated with a high risk of vascular dementia [1, 2]. Type-2 diabetes mellitus (T2DM) is a well-established risk factor for cerebrovascular diseases, such as ischemic stroke [3, 4]. Recent studi...
Rene´ IF de Coo6, Jan C den Hollander7, Renske Oegema1, Douglas B Gould4 and Grazia MS Mancini*,1 Familial porencephaly, leukoencephalopathy and small-vessel disease belong to the spectrum of disorders ascribed to dominant mutations in the gene encoding for type IV collagen alpha-1 (COL...
(AS), any ischemic stroke (AIS) and small vessel stroke (SVS). The WMH locus on chromosome 13 (top SNP: rs11838776) was shared between WMH and SVS. These two loci were not significantly associated at GWAS significance with SVS in the MEGASTROKE study (rs17433120:p = 2.059 ×...
They are patches of fibrinous exudate forming on the surface of colonic mucosa injured byC. difficiletoxin. Necrosis of the surface epithelium and mucosal blood vessel injury lead to an exudation of fibrinogen, which is polymerized into fibrin. Fibrin mixed with the mucus fro...
Alzheimer’s disease and small vessel ischemic disease frequently co-exist in the aging brain. However, pathogenic links between these 2 disorders are yet to be identified. Therefore we used Taqman genotyping, exome and RNA sequencing to investigate Alzh
Alzheimer’s disease; biomarker; cerebral small vessel diseases; predementia; serum; TNF-receptor 1; tumor necrosis factor; vascular cognitive impairment1. Introduction Alzheimer’s disease (AD) and vascular dementia (VaD) are the two most common forms of dementia [1]. AD is a neurodegenerative ...