DTI-MRI measurements record signals from the motion of water molecules in small imaging volumes (voxels). Their sensitivity is associated with the influence of microstructural alterations impacted by TBI41. T2-weighted MRI scans detected increased extracellular fluid in TBI brain42. Indeed, our presen...
Subcortical ischemic vascular disease: roles of oligodendrocyte function in experimental models of subcortical white-matter injury. J Cereb Blood Flow Metab. 2016;36:187–98. Article CAS PubMed PubMed Central Google Scholar Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical ...
Data regarding gut-brain associations and SVD are now emerging. Systemic endotoxin is used in murine experiments to study brain vascular inflammation and microbleed formation [81,82]. A recent report in a Chinese patient cohort found that ischemic stroke and transient ischemic attack correlated with ...
Although sample size was small (∼20 patients per group), the study demonstrated development of ischemic WM changes on dialysis which were more pro- nounced in patients with increased intradialytic hemodynamic instability. Patients who were dialyzed at 0.5 °C below core body temperature showed ...
dressing, walking and golf playing were also noted. The following year, he was diagnosed with Parkinson’s disease, and was prescribed Levodopa. A nuclear medicine DAT scan, however, was normal. Brain MRI demonstrated generalized cerebral atrophy and small vessel white matter ischemic changes. The...
Thus, it is established as a universal marker for neurons. NeuN markers can facilitate the assessment of ganglion cell tumors and hamartomas, hypoxic–ischemic damage, neuronal migration disorders, neurodegenerative diseases, epilepsy, etc. However, a few neuronal cell types are devoid of staining ...