Del C Valdes Hernandez M, Royle NA, Corley J, Munoz Maniega S, Pattie A, Dickie DA, Staals J, et al. Impact of small vessel disease in the brain on gait and balance. Sci Rep. 2017; 7:...
Global small vessel disease brain changes predict cognitive declineCerebrovascular disordersDementiaPrognosisdoi:10.1038/s41582-019-0296-8Ian FyfeNature Reviews Neurology
Small vessel ischemic disease can present itself in mild, moderate, or severe forms. Most older adults, particularly those with a mild form of the disease, are asymptomatic; that is, they show no symptoms of the disease even when there are visible damage areas (through MRI scan) in the br...
In addition to intraparenchymal hemorrhage, the development of nontraumatic, convexity subarachnoid hemorrhage (SAH) due to cerebral small vessel disease can also be seen when accounting for the manifestations of CAA [33]. Symptoms are usually focal neurological deficits that can wax and wane recurrent...
dyspnea symptoms and exacerbations[17]. The chronic bronchitis phenotype seemed to have less influence although numbers of COPD subjects conferring this phenotype were low[17]. Because small vessel disease can lead to thrombosis and subsequent stroke due to lipohyalinosis, fibrinoid degeneration or athe...
small vessel cerebral disease with or without ocular anomalies caused by COL4A1 mutations, is likely an underrecognized cause of perinatal stroke. The pattern of abnormalities reported herein should prompt strong consideration for diagnosis and molecular testing....
Loss of white matter integrity is associated with gait disorders in cerebral small vessel disease. Brain 134 (1), 73–83. http://dx.doi.org/10.1093/brain/ awq34321156660. De Leeuw, F.E., de Groot, J.C., Achten, E., Oudkerk, M., Ramos, L.M., Heijboer, ...
Association of type 2 diabetes with depression, brain atrophy, and reduced fine motor speed in a 60- to 64-year-old community sample. brain atrophy and poor motor function in 60–64 year olds, independent of depression, vascular risk factors, and small vessel disease of the brain.doi... ...
These were analysed to answer three primary questions: first, is there a relationship between whole brain atrophy and magnetic resonance imaging markers of small vessel disease (white matter hyperintensities or lacune volume)? Second, is there regional variation within the cerebral white matter in ...
Purpose This study aims to investigate the alterations of brain volumetry and associated structural covariance at lobar level in cerebral small-vessel disease (CSVD) with and without cognitive impairment. Method Twenty-seven CSVD patients with mild cognitive impairment (CSVD-MCI), 37 CSVD patients ...