Small vessel disease of the brain could be clinically silent, or manifested through a heterogeneous spectrum of diseases, where cognitive decline and stroke-related symptoms are the most common ones. Prevention and therapy are centered around vascular risk factor control, physically and cognitively ...
small vessel disease Acronyms Any of multiple small cerebral infarcts in the corona radiata, internal capsule, striatum, thalamus, basis pontis, and/or cerebellum, occasionally preceded by transient symptoms, due to occlusion or stenosis of small penetrating branches of the middle and posterior cerebral...
To investigate whether severity and progression of periventricular and deep white matter lesions (WML) and lacunar infarcts were associated with progression of brain atrophy.Within the SMART-MR study, a prospective cohort on MRI changes in patients with symptomatic atherosclerotic disease, 565 patients ...
small vessel cerebral disease with or without ocular anomalies caused by COL4A1 mutations, is likely an underrecognized cause of perinatal stroke. The pattern of abnormalities reported herein should prompt strong consideration for diagnosis and molecular testing....
Depression and brain aging may occur simultaneously, and elevated symptoms of depression may affect the brain through small vessel disease, a longitudinal study of older adults suggested. Greater depressive symptoms -- defined as a Center of Epidemiological Studies Depression Scale score of ≥16 -- ...
Introduction: Not only is small vessel disease (SVD) common, especially in older individuals, it often occurs silently and manifests insidiously, with the result that the scope of the problem is under-recognized. The manifestations of SVD are widespread, with an impact on psychiatric status, qual...
Objectives to explore the association between cerebral small﹙essel diseases (CSVDs) and motor symptoms in Parkinson's disease (PD). Methods 137 PD patients were recruited into the study. Detailed motor symptoms, including tremor, rigidity, bradykinesia, and axial impairment, were evaluated using Uni...
this study was to explore the differences in cognitive and neurological functions between cerebral small vessel disease (CSVD) rats and normal rats, as well as to study the Toll- like receptor 4 (TLR4) expression in the hippocampus of CSVD rats to understand its role in this brain structure....
Cerebral small vessel disease (SVD) is a frequent finding on CT and MRI scans of elderly people and is related to vascular risk factors and cognitive and motor impairment, ultimately leading to dementia or parkinsonism in some. In general, the relations are weak, and not all subjects with SVD...
摘要 Cerebral small vessel disease is a neurological disease that affects the brain microvasculature and which is c...展开更多 作者 Ruxue Jia Gemma Solé-Guardia Amanda J.Kiliaan 机构地区 Department of Medical Imaging 出处 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第6期1233-1240,共...