cerebralarteriesCerebralTo the Editor:Cerebral small vessel disease(CSVD)refers to a wide spectrum of pathological processes,which affects the small arteries,arterioles,venous,and capillaries in the brain.This disease causes cognitive,psychological,and physical disabilities and is responsible for up to 45...
Cerebral small vessel disease (CSVD) is defined as a group of CSVD, in which cerebral small arteries, arterioles, capillaries, venules, small veins are attributed to atherosclerotic, genetic, idiopathic, infectious, immune-mediated or other secondary etiologies1. The age-related CSVD includes deep ...
With the increase in life expectancy, age-related diseases are anticipated to cause an enormous burden on health care and social systems. Cerebral small vessel disease (cSVD) contributes to cognitive impairment and dementia in the elderly, with characteristic early deficits in information processing and...
Cerebral small vessel disease (SVD) is a frequent finding on CT and MRI scans of elderly people and is related to vascular risk factors and cognitive and motor impairment, ultimately leading to dementia or parkinsonism in some. In general, the relations are weak, and not all subjects with SVD...
Small Vessel Cerebrovascular Pathology Identified by Magnetic Resonance Imaging Is Prevalent in Alzheimer's Disease and Mild Cognitive Impairment: A Potent... magnetic resonance imagingneuropsychological testingsmall vessel pathologyThere is evidence that Alzheimer's disease (AD) has significant cerebrovascular...
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The continued increase in global life expectancy predicts a rising prevalence of age-related cerebral small vessel diseases (CSVD), which requires a better understanding of the underlying molecular mechanisms. In recent years, the concept of "inflammaging" has attracted increasing attention. It refers ...
Life expectancy in adults with congenital heart disease (ACHD) has increased. As these patients grow older, they experience aging-related diseases more than their healthy peers. To better characterize this field, we launched the multi-disciplinary BACH (Brain Aging in Congenital Heart disease) San...
Late life cognitive control deficits are accentuated by white matter disease burden. Brain 134, 1673–1683 (2011). Article PubMed PubMed Central Google Scholar Papma, J. M. et al. The influence of cerebral small vessel disease on default mode network deactivation in mild cognitive impairment....
predicted life expectancy of at least 3 months and adequate organ function. Key exclusion criteria included previous therapy with anti-angiogenic drugs or other PD-L1 inhibitors; brain metastasis (except for asymptomatic, or stable brain metastases after previous therapy) and/or cancerous meningitis...