小分子抑制剂 小分子抑制剂(Inhibitors)在化学生物学中具有重要的地位。作为一类具有特定功能的化合物,小...
(SND1), which is required to sustain breast cancer progression in established tumors. We performed a small-molecule compound screening to identify a class of specific inhibitors that disrupts the protein–protein interaction (PPI) between MTDH and SND1 and show that our lead candidate compounds C...
Small Molecule Inhibitorsdoi:10.1007/3-540-29623-9_8732Small molecule inhibitors are chemical compounds that bind the active site of a protein, and inhibit either enzyme activity or protein-protein interactions. Much effort is going into screening large......
management of organic impurities in small molecule medicinal products deriving safe limits for use in early development.小分子有机杂质管理医药产品推导安全限制用于早期发展 热度: Small-Molecule Inhibitors of GSK-3 Structural Insights and Their Application to Alzheimer´s Disease Models ...
Small-Molecule Inhibitorsdoi:10.1007/978-3-642-16483-5_5375Refers to a class of drugs specifically designed to inhibit certain proteins (such as kinases) in the cell that have been implicated in disease.Springer Berlin Heidelberg
Santoro, M., Carlomagno, F. Drug Insight: small-molecule inhibitors of protein kinases in the treatment of thyroid cancer.Nat Rev Endocrinol2, 42–52 (2006). https://doi.org/10.1038/ncpendmet0073 Download citation Received04 August 2005 ...
[translate] aconceptual skill 概念性[translate] aHelp yourself to some coffee 帮助 你自己 一些 咖啡[translate] acharacterize two small molecule inhibitors 描绘二种小分子抗化剂[translate]
1.The Discovery of Novel Caspse-1 Inhibitors;新型Caspase-1小分子抑制剂的发现 2.Discovery and Characterization of CDC25B Inhibitors;CDC25B小分子抑制剂的发现及评价 3.Design and discovery of novel small-molecule inhibitor of CDK9新型CDK9小分子抑制剂的设计和发现 4.Design and Synthesis of Small-M...
Small molecule inhibitors of necrosisThe invention features methods for decreasing necrosis. The invention also features methods for treating a subject with a condition in which necrosis occurs. The invention further features chemical compounds used to decrease necrosis.doi:WO2001028493 A3Junying Yuan...
Small molecule inhibitors of methionine aminopeptidase type 2 (MetAP-2). The protein processing enzyme, methionine aminopeptidase-2 (MetAP-2), has been identified as a molecular target of fumagillin and its derivative, TNP-470, ... Garrabrant TTuman RLudovici DTominovich RSimoneaux RGalemmo R...