With regard to morphology, biology, and therapy it seems justified to consider small cell lung carcinoma (SCLC) separately from the other main forms of lung carcinoma (squamous cell, adenocarcinoma, large cell). This is expressed by the rough division of lung cancers into the small cell and ...
Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenografts Article Open access 19 April 2022 Aggressive early-stage lung adenocarcinoma is characterized by epithelial cell plasticity with acquirement of stem-like traits and immune evasion phenotype Article 25...
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Small cell lung cancer (SCLC) is a rapidly proliferating, biologically aggressive form of lung cancer that has a short survival without treatment.61 These tumors probably arise from neuroendocrine cells, which contain neurosecretory granules, and may secrete peptide hormones.14 SCLC is associated...
(SCLC, or small cell lung carcinoma, also formerly called oat cell cancer) andnon-small-cell lung cancer(NSCLC). Most lung cancers are NSCLC, including squamous cell carcinomaand adenocarcinomaof the lung. Small-cell lung cancer accounts for only approximately 15% of all cases of lung cancer....
What is non-small cell lung cancer?Non-small cell lung cancer (NSCLC) is the most common type of lung cancer.What are the subtypes of NSCLC?Squamous cell carcinoma is found in cells that line the airways of the lungs. It is usually found in the middle of the lung. Adenocarcinoma is ...
肺癌分为小细胞肺癌(small cell lung cancer,SCLC)和非小细胞肺癌(non-small cell lung cancer,NSCLC),其中NSCLC占约85%,5年生存率只有不到20% [1,2] 。由于肺癌的早期临床症状不明显,诊断时多为中晚期,极大地提高了诊疗的难度和患者的死亡率。虽然临床常采用癌胚抗原(carcinoembryonic antigen,CEA)、神经元...
Noncoding RNAs such as circular RNAs (circRNAs) are abundant in the human body and influence the occurrence and development of various diseases. Non-small cell lung cancer (NSCLC) is one of the most common malignant cancers. Information on the functions
Non-small-cell lung cancer (NSCLC) is the most common type of cancer affecting the lungs. The diverse types of NSCLC are characterized by cancer cells that grow and spread in different ways. The three most common forms of NSCLC are adenocarcinoma, squamous cell carcinoma and large cell carcino...
significantly diminishes the sensitivity of the lung adenocarcinoma cell line carrying the BRAF V600E mutation (HCC364) to vemurafenib and trametinib. Further mechanistic studies have revealed that YAP can promote the resistance of lung cancer cells to RAF and MEK inhibitors by upregulating the ...